Pulmonary myxoid leiomyosarcoma.

Source:http://linkedlifedata.com/resource/pubmed/id/8581153

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General Info

Authors

Sato K, Suzuki E, Fukuda T, Naito M, Ohnishi Y, Koizumi N, Emura I, Hirono T

Affiliation

Second Department of Pathology, Niigata University School of Medicine, Japan.

Abstract

A primary myxoid leiomyosarcoma arising from the peripheral bronchus of the right middle lobe was removed from a 20 year old man and examined by immunohistochemistry and electron microscopy. The tumor was well circumscribed, yellow-whitish focal polypoid growth into the bronchial lumen and consisted of spindle cells with abundant myxoid substance in the stroma. Intrapulmonary metastasis, invasion to the bronchial wall and a few mitotic figures were found. Immunohistochemically, several, but not all, tumor cells were positive against anti-vimentin, anti-S-100 protein, anti-myosin and anti-muscle specific actin. Ultrastructurally, tumor cells had thin filaments with dense bodies, pinocytic vesicles and discontinuous basal lamina. These findings indicate a myoxoid variant of leiomyosarcoma arising from mesenchyme in the peribronchial area.

PMID
8581153

Publication types

Case Reports