pubmed-article:8579476 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0021359 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0025266 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0037868 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0040106 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C1979844 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C1096776 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C0206012 | lld:lifeskim |
pubmed-article:8579476 | lifeskim:mentions | umls-concept:C1516240 | lld:lifeskim |
pubmed-article:8579476 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:8579476 | pubmed:dateCreated | 1996-3-14 | lld:pubmed |
pubmed-article:8579476 | pubmed:abstractText | Thymosin alpha-1 (T alpha 1) significantly enhances the fertilizability of sperm from fertile men by increasing capacitation and/or acrosome reaction. The present study was conducted to investigate the effect of T alpha 1 on fertilizing capacity of sperm of infertile men using the sperm penetration assay (SPA) in a multicenter clinical trial. T alpha 1 significantly (p = .0006 to < .0001) increased (31 to 45%) fertilizing capacity of sperm of 76% (50/68) of infertile men as defined by the sperm penetration index in SPA. The enhancing effect of T alpha 1 and the degree of enhancement depended on the T alpha 1 concentration in the seminal plasma, since these parameters showed a significant intercorrelation (r = .65 to .74, p = .039 to .01). It would appear that T alpha 1 may have clinical application in the diagnosis and treatment of male infertility especially mediated through defective sperm function. | lld:pubmed |
pubmed-article:8579476 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8579476 | pubmed:language | eng | lld:pubmed |
pubmed-article:8579476 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8579476 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8579476 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8579476 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8579476 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8579476 | pubmed:issn | 0148-5016 | lld:pubmed |
pubmed-article:8579476 | pubmed:author | pubmed-author:MengeA CAC | lld:pubmed |
pubmed-article:8579476 | pubmed:author | pubmed-author:RaoV DVD | lld:pubmed |
pubmed-article:8579476 | pubmed:author | pubmed-author:SaccoAA | lld:pubmed |
pubmed-article:8579476 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8579476 | pubmed:volume | 35 | lld:pubmed |
pubmed-article:8579476 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8579476 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8579476 | pubmed:pagination | 149-54 | lld:pubmed |
pubmed-article:8579476 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:8579476 | pubmed:meshHeading | pubmed-meshheading:8579476-... | lld:pubmed |
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pubmed-article:8579476 | pubmed:articleTitle | Treatment with thymosin alpha-1 increases fertilizing capacity of sperm of infertile men: a multicenter trial. | lld:pubmed |
pubmed-article:8579476 | pubmed:affiliation | Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Bronx, New York 10461, USA. | lld:pubmed |
pubmed-article:8579476 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8579476 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:8579476 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:8579476 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:8579476 | pubmed:publicationType | Multicenter Study | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8579476 | lld:pubmed |