pubmed-article:8572505 | pubmed:abstractText | Lorazepam and oxazepam are benzodiazepine which differ by the presence, or not, of chlorine atom on the phenyl ring. These molecules are able of chemical and thermal degradation with water intramolecular elimination between hydroxy and amine functional group and formation of carboxaldehyde quinazoline. These substances characterise lorazepam and oxazepam by their thermal behaviour and melting temperature by heating and cooling cycles. | lld:pubmed |