| pubmed-article:8556058 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8556058 | lifeskim:mentions | umls-concept:C0206667 | lld:lifeskim |
| pubmed-article:8556058 | lifeskim:mentions | umls-concept:C0039082 | lld:lifeskim |
| pubmed-article:8556058 | lifeskim:mentions | umls-concept:C0678226 | lld:lifeskim |
| pubmed-article:8556058 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8556058 | pubmed:dateCreated | 1996-2-28 | lld:pubmed |
| pubmed-article:8556058 | pubmed:abstractText | We demonstrated the functional evaluation of adrenal incidentaloma in 8 patients who had no abnormal finding associated with Cushing's syndrome. Adrenal tumors were incidentally discovered by abdominal echogram in 5 patients and by computed tomography (CT) in 3 patients. Serum cortisol levels and urinary excretion of 17-hydroxycorticosteroids (17-OHCS) were within normal limits in four of 8 patients. Urinary excretion of free cortisol was also within normal limits except for patient 8. Urinary excretion of 17-OHCS, however, was not suppressed by dexamethasone administration in five of 8 patients. Excretion of urinary 17-OHCS did not increase in response to metyrapone in 3 of 4 dexamethasone-insuppressible patients, but increased in 3 dexamethasone-suppressible ones. Serum cortisol increased in response to exogenous ACTH in all 6 patients examined. 131I-Adosterol accumulation was found in only the tumor side in 7 patients and bilaterally in one patient. Adrenalectomy was done in 7 patients, and microscopic findings showed adrenocortical adenoma. Serum cortisol was significantly suppressed in response to dexamethasone in the post-operative stage in all 7 patients examined. These results indicate that these adrenal incidentalomas seem to have a cortisol over-production which is dexamethasone-insuppressible and ACTH-dependent, and that they can be classified as "Pre-Cushing's Syndrome." | lld:pubmed |
| pubmed-article:8556058 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8556058 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8556058 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8556058 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8556058 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:8556058 | pubmed:issn | 0918-8959 | lld:pubmed |
| pubmed-article:8556058 | pubmed:author | pubmed-author:SaitoTT | lld:pubmed |
| pubmed-article:8556058 | pubmed:author | pubmed-author:OkadaKK | lld:pubmed |
| pubmed-article:8556058 | pubmed:author | pubmed-author:IshikawaSS | lld:pubmed |
| pubmed-article:8556058 | pubmed:author | pubmed-author:TsuboiYY | lld:pubmed |
| pubmed-article:8556058 | pubmed:author | pubmed-author:FujisawaGG | lld:pubmed |
| pubmed-article:8556058 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8556058 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:8556058 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8556058 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8556058 | pubmed:pagination | 509-16 | lld:pubmed |
| pubmed-article:8556058 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:meshHeading | pubmed-meshheading:8556058-... | lld:pubmed |
| pubmed-article:8556058 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8556058 | pubmed:articleTitle | Possible pre-Cushing's syndrome due to an adrenal adenoma incidentally discovered. | lld:pubmed |
| pubmed-article:8556058 | pubmed:affiliation | Department of Medicine, Jichi Medical School, Tochigi, Japan. | lld:pubmed |
| pubmed-article:8556058 | pubmed:publicationType | Journal Article | lld:pubmed |
