| pubmed-article:8537381 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0022658 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0055363 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8537381 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8537381 | pubmed:issue | 52 | lld:pubmed |
| pubmed-article:8537381 | pubmed:dateCreated | 1996-2-8 | lld:pubmed |
| pubmed-article:8537381 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8537381 | pubmed:abstractText | We have cloned a novel member of the CLC chloride channel family from rat brain, rCLC-5. The cDNA predicts a 83-kDa protein belonging to the branch including CLC-3 and CLC-4, with which it shares approximately 80% identity. Expression of rCLC-5 in Xenopus oocytes elicits novel anion currents. They are strongly outwardly rectifying and have a conductivity sequence of NO3- > Cl- > Br- > I- >> glutamate-. Although CLC-5 has consensus sites for phosphorylation by protein kinase A, raising the intracellular cAMP concentration had no effect on these currents. Currents were also unchanged when rCLC-5 was coexpressed with rCLC-3 and rCLC-4, either singly or in combination. rCLC-5 is expressed predominantly in kidney and also in brain, lung, and liver. Along the nephron, rCLC-5 message is detectable in all tubule segments investigated, but expression in the glomerulus and the S2 segment of the proximal tubule is low. | lld:pubmed |
| pubmed-article:8537381 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8537381 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8537381 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8537381 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8537381 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8537381 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:8537381 | pubmed:author | pubmed-author:VandewalleAA | lld:pubmed |
| pubmed-article:8537381 | pubmed:author | pubmed-author:BensMM | lld:pubmed |
| pubmed-article:8537381 | pubmed:author | pubmed-author:JentschT JTJ | lld:pubmed |
| pubmed-article:8537381 | pubmed:author | pubmed-author:SteinmeyerKK | lld:pubmed |
| pubmed-article:8537381 | pubmed:author | pubmed-author:SchwappachBB | lld:pubmed |
| pubmed-article:8537381 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8537381 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:8537381 | pubmed:volume | 270 | lld:pubmed |
| pubmed-article:8537381 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8537381 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8537381 | pubmed:pagination | 31172-7 | lld:pubmed |
| pubmed-article:8537381 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:8537381 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8537381 | pubmed:articleTitle | Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease. | lld:pubmed |
| pubmed-article:8537381 | pubmed:affiliation | Center for Molecular Neurobiology, Hamburg University, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:8537381 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8537381 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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