pubmed-article:853287 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0034144 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0521119 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0025251 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0032821 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:853287 | lifeskim:mentions | umls-concept:C0597277 | lld:lifeskim |
pubmed-article:853287 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:853287 | pubmed:dateCreated | 1977-6-11 | lld:pubmed |
pubmed-article:853287 | pubmed:abstractText | We used open tip microelectrodes containing a K+-sensitive liquid ion exchanger to determine directly the intracellular K+ activity in beating canine cardiac Purkinje fibers. For preparations superfused with Tyrode's solution in which the K+ concentration was 4.0 mM, intracellular K+ activity (ak) was 130.0+/-2.3 mM (mean+/-SE) at 37 degrees C. The calculated K+ equilibrium potential (EK) was -100.6+/-0.5 mV. Maximum diastolic potential (ED) and resting transmembrane potential (EM) were measured with conventional microelectrodes filled with 3 M KCl and were -90.6+/-0.3 and -84.4+/-0.4 mV, respectively. When [K+]o was decreased to 2.0 mM or increased to 6.0, 10.0, and 16.0 mM, ak remained the same. At [K+]o=2.0, ED was -97.3+/-0.4 and Em -86.0+/-0.7 mV; at [K+]o=16.0, ED fell to -53.8+/-0.4 mV and Em to the same value. Over this range of values for [K+]o, EK changed from -119.0+/-0.3 to -63.6+/-0.2 mV. These values for EK are consistent with those previously estimated indirectly by other techniques. | lld:pubmed |
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pubmed-article:853287 | pubmed:language | eng | lld:pubmed |
pubmed-article:853287 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:853287 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:853287 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:853287 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:853287 | pubmed:month | Apr | lld:pubmed |
pubmed-article:853287 | pubmed:issn | 0022-1295 | lld:pubmed |
pubmed-article:853287 | pubmed:author | pubmed-author:HoffmanB FBF | lld:pubmed |
pubmed-article:853287 | pubmed:author | pubmed-author:RosenM RMR | lld:pubmed |
pubmed-article:853287 | pubmed:author | pubmed-author:MiuraD SDS | lld:pubmed |
pubmed-article:853287 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:853287 | pubmed:volume | 69 | lld:pubmed |
pubmed-article:853287 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:853287 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:853287 | pubmed:pagination | 463-74 | lld:pubmed |
pubmed-article:853287 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:853287 | pubmed:year | 1977 | lld:pubmed |
pubmed-article:853287 | pubmed:articleTitle | The effect of extracellular potassium on the intracellular potassium ion activity and transmembrane potentials of beating canine cardiac Purkinje fibers. | lld:pubmed |
pubmed-article:853287 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:853287 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:853287 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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