| pubmed-article:8530141 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8530141 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
| pubmed-article:8530141 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:8530141 | lifeskim:mentions | umls-concept:C0108685 | lld:lifeskim |
| pubmed-article:8530141 | pubmed:issue | 2-4 | lld:pubmed |
| pubmed-article:8530141 | pubmed:dateCreated | 1996-2-1 | lld:pubmed |
| pubmed-article:8530141 | pubmed:abstractText | The C/EBP proteins form a family of transcription factors with at least seven members. These proteins consist of three structural components which include a C-terminal leucine-zipper, a basic DNA-binding region and a N-terminal transactivating region. Dimerization through the leucine-zipper leads to formation of homo- and heterodimers which then bind with their two basic regions to often non-symmetric DNA-sequences in the promoter/enhancer regions of a variety of genes. Expression of C/EBP is prominent in adipocytes, hepatocytes and monocytes/macrophages, and here these proteins are involved in tissue-specific gene expression. Target genes for C/EBP include those for acute phase response genes in liver cells and for cytokine genes in monocytes/macrophages. Therefore, intervention at the level of C/EBP transcription factors may prove effective in controlling immune response. | lld:pubmed |
| pubmed-article:8530141 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8530141 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530141 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8530141 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8530141 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8530141 | pubmed:issn | 0171-2985 | lld:pubmed |
| pubmed-article:8530141 | pubmed:author | pubmed-author:WedelAA | lld:pubmed |
| pubmed-article:8530141 | pubmed:author | pubmed-author:Ziegler-Heitb... | lld:pubmed |
| pubmed-article:8530141 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8530141 | pubmed:volume | 193 | lld:pubmed |
| pubmed-article:8530141 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8530141 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8530141 | pubmed:pagination | 171-85 | lld:pubmed |
| pubmed-article:8530141 | pubmed:dateRevised | 2005-11-16 | lld:pubmed |
| pubmed-article:8530141 | pubmed:meshHeading | pubmed-meshheading:8530141-... | lld:pubmed |
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| pubmed-article:8530141 | pubmed:meshHeading | pubmed-meshheading:8530141-... | lld:pubmed |
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| pubmed-article:8530141 | pubmed:meshHeading | pubmed-meshheading:8530141-... | lld:pubmed |
| pubmed-article:8530141 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8530141 | pubmed:articleTitle | The C/EBP family of transcription factors. | lld:pubmed |
| pubmed-article:8530141 | pubmed:affiliation | Institute for Immunology, University of Munich, Germany. | lld:pubmed |
| pubmed-article:8530141 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8530141 | pubmed:publicationType | Review | lld:pubmed |
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