Linked Life Data

8525379

Source:http://linkedlifedata.com/resource/pubmed/id/8525379

Statements in which the resource exists.
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pubmed-article:8525379pubmed:abstractTextThe relative locations of several chromosomes within wheel-shaped prometaphase chromosome rosettes of human fibroblasts and HeLa cells were determined with fluorescence hybridization. Homologs were consistently positioned on opposite sides of the rosette, which suggests that chromosomes are separated into two haploid sets, each derived from one parent. The relative locations of chromosomes on the rosette were mapped by dual hybridizations. The data suggest that the chromosome orders within the two haploid sets are antiparallel. This chromosome arrangement in human cells appears to be both independent of cell type- and species-specific and may influence chromosome topology throughout the cell cycle.lld:pubmed
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pubmed-article:8525379pubmed:articleTitlePrecise spatial positioning of chromosomes during prometaphase: evidence for chromosomal order.lld:pubmed
pubmed-article:8525379pubmed:affiliationDepartment of Molecular Biology, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Stratford 08084, USA.lld:pubmed
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