| pubmed-article:8522112 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0008328 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0399805 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8522112 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8522112 | pubmed:issue | 8-9 | lld:pubmed |
| pubmed-article:8522112 | pubmed:dateCreated | 1996-1-25 | lld:pubmed |
| pubmed-article:8522112 | pubmed:abstractText | Cholecystokinin (CCK) is a peptide released after feeding. Until now, CCK gene expression has been studied only on sacrified animals on mucosa scrapped off the duodenum. OBJECTIVE--The aim of this study was to assess CCK-mRNA detection on duodenal biopsy specimens in subjects undergoing gastrointestinal endoscopy. METHODS--Six biopsy specimens were taken from 6 healthy subjects, a) after a 12-h overnight fast and b) 6 or 12 h after a fat meal, and inducing a CCK release. CCK-mRNA was analyzed by Northern blot. RESULTS--Plasma CCK levels increased from basal levels of 0.5 +/- 0.1 pmole/L to 8.2 +/- 1.5 pmole/L 10 min after the meal. The fasting CCK-mRNA levels were 44.0 +/- 0.6% and the post-prandial levels increased to 74.0 +/- 6.0% at 6 h and decreased to 47.5 +/- 0.5% at 12 h. CONCLUSIONS--Detection of CCK gene expression in human duodenal biopsy specimens is feasible. Stimulation of CCK release after a meal is followed by an increase in CCK-mRNA in the duodenal mucosa. | lld:pubmed |
| pubmed-article:8522112 | pubmed:language | fre | lld:pubmed |
| pubmed-article:8522112 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8522112 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8522112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8522112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8522112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8522112 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8522112 | pubmed:issn | 0399-8320 | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:GalmicheJ PJP | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:LerayVV | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:BlottièreH... | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:Bruley des... | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:ZerbibFF | lld:pubmed |
| pubmed-article:8522112 | pubmed:author | pubmed-author:BentouimouNN | lld:pubmed |
| pubmed-article:8522112 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8522112 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:8522112 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8522112 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8522112 | pubmed:pagination | 659-63 | lld:pubmed |
| pubmed-article:8522112 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:meshHeading | pubmed-meshheading:8522112-... | lld:pubmed |
| pubmed-article:8522112 | pubmed:articleTitle | [Expression of the gene of cholecystokinin. Demonstration from duodenal biopsies in man]. | lld:pubmed |
| pubmed-article:8522112 | pubmed:affiliation | Centre de Recherche en Nutrition Humaine de Nantes, CHU G.-et-R.-Laennec. | lld:pubmed |
| pubmed-article:8522112 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8522112 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:8522112 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
