[Cutaneous candidiasis due to Candida parapsilosis occurring in the course of idiopathic aplastic anemia].

Source:http://linkedlifedata.com/resource/pubmed/id/8519395

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Authors

Richard-Lenoble D, Grangeponte MC, Machet L, GRAY DH, De Muret A, Machet MC, Cochelin N, Stéphanov E

Affiliation

Service d'Anatomie Pathologique, CHU Trousseau, Tours.

Abstract

Candida parapsilosis is a very common and saprophytic fungus. Its pathogenic role has been reported in intensive care units after invasive instrumentations. We report a case of dermal candidiasis due to Candida parapsilosis occurring in an immunocompromised patient suffering from aplastic anemia treated with corticosteroids. The histopathological aspect was non specific, showing a polymorphous granulomatous reaction in the middermis. Findings of periodic acid-Schiff and Grocott-Gomori stains revealed a large number of pseudohyphae and spores. Candida parasilosis was cultured from a skin biopsy. The route of skin infection is discussed: direct inoculation or septic localization after fungemia.

PMID
8519395

Publication types

English Abstract; Case Reports