pubmed-article:851476 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:851476 | lifeskim:mentions | umls-concept:C0319116 | lld:lifeskim |
pubmed-article:851476 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
pubmed-article:851476 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
pubmed-article:851476 | lifeskim:mentions | umls-concept:C1514849 | lld:lifeskim |
pubmed-article:851476 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:851476 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:851476 | pubmed:dateCreated | 1977-3-31 | lld:pubmed |
pubmed-article:851476 | pubmed:abstractText | The linear duplex replicative form (RF) DNA of the parvovirus H-1 has been characterized with respect to cleavage by the bacterial restriction endonuclease of Escherichia coli, EcoRI. RF DNA has a single cleavage site 0.22 genome length from the left end of the molecule. The molecular weight of H-1 RF DNA determined by gel electrophoresis is 3.26 X 10(6). H-1 RF DNA has been found to dimerize by hydrogen-bounded linkage at the molecular left end, and in some molecules the viral strand is covalently linked to the complementary strand. Some 10% of monomeric RF DNA also has a covalent linkage between the viral and complementary strands at the left end. The EcoRI-B fragment, containing the left end of the RF molecule, appears to be a replication terminus by its labeling characteristics for both RF and progeny DNA synthesis. These findings suggest that the left end of H-1 RF DNA has some type of "turn-around" structure and that this end is not an origin for DNA synthesis. | lld:pubmed |
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pubmed-article:851476 | pubmed:language | eng | lld:pubmed |
pubmed-article:851476 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:851476 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:851476 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:851476 | pubmed:month | Feb | lld:pubmed |
pubmed-article:851476 | pubmed:issn | 0022-538X | lld:pubmed |
pubmed-article:851476 | pubmed:author | pubmed-author:RhodeS LSL3rd | lld:pubmed |
pubmed-article:851476 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:851476 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:851476 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:851476 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:851476 | pubmed:pagination | 694-712 | lld:pubmed |
pubmed-article:851476 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:851476 | pubmed:year | 1977 | lld:pubmed |
pubmed-article:851476 | pubmed:articleTitle | Replication process of the parvovirus H-1. VI. Characterization of a replication terminus of H-1 replicative-form DNA. | lld:pubmed |
pubmed-article:851476 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:851476 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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