| pubmed-article:8513140 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C0205421 | lld:lifeskim |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:8513140 | lifeskim:mentions | umls-concept:C1883709 | lld:lifeskim |
| pubmed-article:8513140 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8513140 | pubmed:dateCreated | 1993-7-22 | lld:pubmed |
| pubmed-article:8513140 | pubmed:abstractText | Exposure of primary murine cortical neuron cultures to N-methyl-D-aspartate (NMDA) resulted in neuronal death as evidenced by release of lactate dehydrogenase (LDH) into the media. The addition of N-nitro-L-arginine (N-Arg) protected the neurons from death in a concentration-dependent manner when added after the NMDA, but not when the N-Arg was present with the NMDA. Protection by N-Arg was lost if L-arginine containing media was added to the cultures prior to the addition of the N-Arg. Treatment of the neurons with kainate prior to NMDA reduced subsequent NMDA-induced damage which was not prevented with N-Arg. These results suggest that delayed production of nitric oxide (NO) contributes to NMDA-induced neuronal damage in culture. | lld:pubmed |
| pubmed-article:8513140 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8513140 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8513140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8513140 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8513140 | pubmed:month | May | lld:pubmed |
| pubmed-article:8513140 | pubmed:issn | 0959-4965 | lld:pubmed |
| pubmed-article:8513140 | pubmed:author | pubmed-author:ReidD ADA | lld:pubmed |
| pubmed-article:8513140 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8513140 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:8513140 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8513140 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8513140 | pubmed:pagination | 566-8 | lld:pubmed |
| pubmed-article:8513140 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:meshHeading | pubmed-meshheading:8513140-... | lld:pubmed |
| pubmed-article:8513140 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8513140 | pubmed:articleTitle | Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage. | lld:pubmed |
| pubmed-article:8513140 | pubmed:affiliation | Biology Department, Fisons Pharmaceuticals, Rochester, NY 14603. | lld:pubmed |
| pubmed-article:8513140 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8513140 | lld:pubmed |
