The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate.

Source:http://linkedlifedata.com/resource/pubmed/id/8510100

J. Med. Chem. 1993 Jun 11 36 12 1716-25

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8510100