| pubmed-article:8495369 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8495369 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:8495369 | lifeskim:mentions | umls-concept:C0023586 | lld:lifeskim |
| pubmed-article:8495369 | lifeskim:mentions | umls-concept:C0002766 | lld:lifeskim |
| pubmed-article:8495369 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:8495369 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:8495369 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8495369 | pubmed:dateCreated | 1993-6-21 | lld:pubmed |
| pubmed-article:8495369 | pubmed:abstractText | Two independent selective breeding programs have developed divergent lines of mice expressing either high and low swim stress-induced analgesia (HA/LA lines; Jastrzebiec, Poland) or high and low levorphanol analgesia (HAR/LAR lines; Portland, OR). In the present study, mice from both programs were tested for both levorphanol analgesia (2 mg/kg) and an opioid-mediated swim stress-induced analgesia (3 min swimming in 32 degrees C water) in the hot-plate test. Mice selected for high and low levorphanol analgesia displayed high and low swim stress-induced analgesia, respectively; mice selected for high and low swim stress-induced analgesia displayed high and low levorphanol analgesia, respectively. This pattern of correlated responses suggests a high degree of common genetic determination in opiate and swim stress-induced analgesia. These findings also suggest that individual differences in analgesic responsiveness to opiate drugs result from genetically determined individual differences in endogenous pain inhibitory mechanisms. | lld:pubmed |
| pubmed-article:8495369 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495369 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8495369 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495369 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8495369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495369 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8495369 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8495369 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:8495369 | pubmed:author | pubmed-author:BelknapJ KJK | lld:pubmed |
| pubmed-article:8495369 | pubmed:author | pubmed-author:SadowskiBB | lld:pubmed |
| pubmed-article:8495369 | pubmed:author | pubmed-author:LiebeskindJ... | lld:pubmed |
| pubmed-article:8495369 | pubmed:author | pubmed-author:MarekPP | lld:pubmed |
| pubmed-article:8495369 | pubmed:author | pubmed-author:MogilJ SJS | lld:pubmed |
| pubmed-article:8495369 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8495369 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:8495369 | pubmed:volume | 608 | lld:pubmed |
| pubmed-article:8495369 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8495369 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8495369 | pubmed:pagination | 353-7 | lld:pubmed |
| pubmed-article:8495369 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:meshHeading | pubmed-meshheading:8495369-... | lld:pubmed |
| pubmed-article:8495369 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8495369 | pubmed:articleTitle | Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalities. | lld:pubmed |
| pubmed-article:8495369 | pubmed:affiliation | Department of Psychology, University of California, Los Angeles 90024. | lld:pubmed |
| pubmed-article:8495369 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8495369 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8495369 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8495369 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8495369 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8495369 | lld:pubmed |
