| pubmed-article:8495206 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0677626 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0010762 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0039635 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:8495206 | lifeskim:mentions | umls-concept:C0162518 | lld:lifeskim |
| pubmed-article:8495206 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8495206 | pubmed:dateCreated | 1993-6-18 | lld:pubmed |
| pubmed-article:8495206 | pubmed:abstractText | Mouse interferon gamma (IFN-G) markedly suppressed 7-ethoxyresorufin o-deethylase (EROD) activity when added at the same time as TCDD in mouse primary hepatocyte cultures. IFN-G, however, had no effect on EROD induction by TCDD in Hepa-1 cells, a mouse hepatoma cell line, or Hepa-1 cells cocultured with Kupffer cells when added directly to the culture. EROD induction by TCDD in Hepa-1 cells was suppressed when cells were cultured with IFN-G pretreated mouse hepatocytes conditioned media. The magnitude of suppression was related to the dose of IFN-G and the density of hepatocytes used for the preparation of the conditioned media. Treatment of the monoclonal antibody against IFN-G to the conditioned media did not block the suppression of EROD induction. The suppressive effect of IFN-G pretreated hepatocytes conditioned media on EROD induction, however, was blocked when the conditioned media was heated or treated with trypsin. These results suggested that IFN-G pretreated mouse hepatocytes may release a soluble protein factor(s) which suppressed the EROD induction by TCDD in Hepa-1 cells. | lld:pubmed |
| pubmed-article:8495206 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8495206 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8495206 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8495206 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8495206 | pubmed:issn | 1039-9712 | lld:pubmed |
| pubmed-article:8495206 | pubmed:author | pubmed-author:YangK HKH | lld:pubmed |
| pubmed-article:8495206 | pubmed:author | pubmed-author:JeongT CTC | lld:pubmed |
| pubmed-article:8495206 | pubmed:author | pubmed-author:JeongH GHG | lld:pubmed |
| pubmed-article:8495206 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8495206 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:8495206 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8495206 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8495206 | pubmed:pagination | 197-202 | lld:pubmed |
| pubmed-article:8495206 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:meshHeading | pubmed-meshheading:8495206-... | lld:pubmed |
| pubmed-article:8495206 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8495206 | pubmed:articleTitle | Mouse interferon gamma pretreated hepatocytes conditioned media suppress cytochrome P-450 induction by TCDD in mouse hepatoma cells. | lld:pubmed |
| pubmed-article:8495206 | pubmed:affiliation | Department of Life Science, Korea Advanced Institute of Science and Technology, Taejon. | lld:pubmed |
| pubmed-article:8495206 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8495206 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8495206 | lld:pubmed |
