pubmed-article:8458524 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C0206131 | lld:lifeskim |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C0042305 | lld:lifeskim |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C0015264 | lld:lifeskim |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:8458524 | lifeskim:mentions | umls-concept:C0136151 | lld:lifeskim |
pubmed-article:8458524 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:8458524 | pubmed:dateCreated | 1993-4-27 | lld:pubmed |
pubmed-article:8458524 | pubmed:abstractText | Vanadate and peroxovanadate were recently reported to exert maximal or even supramaximal (peroxovanadate) insulin-like effects in rat adipocytes. To evaluate the response in human cells, isolated human adipocytes were exposed to insulin or various concentrations of vanadate (0-10 mmol/l) or peroxovanadate (0-5 mmol/l). Neither vanadate nor peroxovanadate affected 125I-insulin binding and insulin sensitivity. Vanadate exerted no apparent effect on 14C-U-glucose uptake, whereas 0.1 mmol/l peroxovanadate exerted a full insulin-like response (p < 0.001). No additive response was observed by combining either vanadate or peroxovanadate with insulin. Peroxovanadate at 0.1 mmol/l was as effective as insulin in inhibiting isoproterenol-stimulated lipolysis. Neither peroxovanadate nor insulin-inhibited lipolysis stimulated by N6-monobutyryl-cAMP, an analogue which is not hydrolysed by the cAMP-phosphodiesterase. It is concluded that peroxovanadate, but not vanadate, elicits a full insulin-like response in human adipocytes. | lld:pubmed |
pubmed-article:8458524 | pubmed:language | eng | lld:pubmed |
pubmed-article:8458524 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8458524 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8458524 | pubmed:month | Feb | lld:pubmed |
pubmed-article:8458524 | pubmed:issn | 0012-186X | lld:pubmed |
pubmed-article:8458524 | pubmed:author | pubmed-author:SmithUU | lld:pubmed |
pubmed-article:8458524 | pubmed:author | pubmed-author:PosnerB IBI | lld:pubmed |
pubmed-article:8458524 | pubmed:author | pubmed-author:LönnrothPP | lld:pubmed |
pubmed-article:8458524 | pubmed:author | pubmed-author:ErikssonJ WJW | lld:pubmed |
pubmed-article:8458524 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8458524 | pubmed:volume | 36 | lld:pubmed |
pubmed-article:8458524 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8458524 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8458524 | pubmed:pagination | 113-6 | lld:pubmed |
pubmed-article:8458524 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:meshHeading | pubmed-meshheading:8458524-... | lld:pubmed |
pubmed-article:8458524 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8458524 | pubmed:articleTitle | Peroxovanadate but not vanadate exerts insulin-like effects in human adipocytes. | lld:pubmed |
pubmed-article:8458524 | pubmed:affiliation | Department of Medicine, University of Göteborg, Sweden. | lld:pubmed |
pubmed-article:8458524 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8458524 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:8458524 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8458524 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8458524 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8458524 | lld:pubmed |