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| pubmed-article:8439318 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8439318 | pubmed:dateCreated | 1993-3-23 | lld:pubmed |
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| pubmed-article:8439318 | pubmed:abstractText | Betacellulin (BTC) is a novel growth factor purified from the conditioned media of mouse pancreatic beta tumor cells and has been found to be a new member of the epidermal growth factor (EGF) family. The cDNA encoding human BTC has been cloned from a cDNA library prepared from human breast adenocarcinoma cell line MCF-7. The nucleotide sequence encodes a polypeptide which consists of 178 amino acid residues including a putative signal sequence, indicating that the structural organization of human BTC is similar to that of mouse BTC. The amino acid sequence of the human BTC precursor protein exhibits 79% similarity with that of the mouse precursor protein. The BTC gene was found to be expressed in several mouse tissues including kidney and liver as well as in a mouse beta tumor cell line and MCF-7 cells, suggesting that BTC might play a physiological role in normal tissues. | lld:pubmed |
| pubmed-article:8439318 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:8439318 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8439318 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8439318 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8439318 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:OnoYY | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:IgarashiKK | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:FolkmanJJ | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:ShinoAA | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:SasadaRR | lld:pubmed |
| pubmed-article:8439318 | pubmed:author | pubmed-author:TaniyamaYY | lld:pubmed |
| pubmed-article:8439318 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8439318 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8439318 | pubmed:volume | 190 | lld:pubmed |
| pubmed-article:8439318 | pubmed:geneSymbol | AR | lld:pubmed |
| pubmed-article:8439318 | pubmed:geneSymbol | EGF | lld:pubmed |
| pubmed-article:8439318 | pubmed:geneSymbol | BTC | lld:pubmed |
| pubmed-article:8439318 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8439318 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8439318 | pubmed:pagination | 1173-9 | lld:pubmed |
| pubmed-article:8439318 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8439318 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8439318 | pubmed:articleTitle | Cloning and expression of cDNA encoding human betacellulin, a new member of the EGF family. | lld:pubmed |
| pubmed-article:8439318 | pubmed:affiliation | Discovery Research Laboratories II, Takeda Chemical Industries, Ltd., Osaka, Japan. | lld:pubmed |
| pubmed-article:8439318 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8439318 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8439318 | pubmed:publicationType | In Vitro | lld:pubmed |
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