| pubmed-article:842986 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:842986 | lifeskim:mentions | umls-concept:C0023895 | lld:lifeskim |
| pubmed-article:842986 | lifeskim:mentions | umls-concept:C1283144 | lld:lifeskim |
| pubmed-article:842986 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:842986 | pubmed:dateCreated | 1977-4-25 | lld:pubmed |
| pubmed-article:842986 | pubmed:abstractText | Kayser-Fleischer rings are pigmented corneal rings at the limbus of the cornea in Descemet's membrane that have been deemed pathognomonic of Wilson's disease. However, we have observed four exceptions in patients with non-Wilsonian liver disease. Three patients had primary biliary cirrhosis and one patient had chronic aggressive hepatitis with cirrhosis. Pigmented corneal rings were seen only by slit-lamp examination. Hepatic, serum, and urinary copper and serum ceruloplasmin levels were significantly elevated in the patients with primary biliary cirrhosis. Radiocopper (64Cu or 67Cu) studies in patients with primary biliary cirrhosis showed plasma disappearance curves which allowed a clear distinction from Wilson's disease in that all three patients with primary biliary cirrhosis showed a secondary rise in radiocopper that presumably represented copper incorporation into ceruloplasmin. In one patient, in whom 64Cu in ceruloplasmin was studied specifically, incorporation was found to be normal. | lld:pubmed |
| pubmed-article:842986 | pubmed:language | eng | lld:pubmed |
| pubmed-article:842986 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:842986 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:842986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:842986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:842986 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:842986 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:842986 | pubmed:issn | 0003-4819 | lld:pubmed |
| pubmed-article:842986 | pubmed:author | pubmed-author:FlemingC RCR | lld:pubmed |
| pubmed-article:842986 | pubmed:author | pubmed-author:McCallJ TJT | lld:pubmed |
| pubmed-article:842986 | pubmed:author | pubmed-author:WahnerH WHW | lld:pubmed |
| pubmed-article:842986 | pubmed:author | pubmed-author:DicksonE RER | lld:pubmed |
| pubmed-article:842986 | pubmed:author | pubmed-author:HollenhorstR... | lld:pubmed |
| pubmed-article:842986 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:842986 | pubmed:volume | 86 | lld:pubmed |
| pubmed-article:842986 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:842986 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:842986 | pubmed:pagination | 285-8 | lld:pubmed |
| pubmed-article:842986 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:842986 | pubmed:meshHeading | pubmed-meshheading:842986-H... | lld:pubmed |
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| pubmed-article:842986 | pubmed:meshHeading | pubmed-meshheading:842986-L... | lld:pubmed |
| pubmed-article:842986 | pubmed:meshHeading | pubmed-meshheading:842986-D... | lld:pubmed |
| pubmed-article:842986 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:842986 | pubmed:articleTitle | Pigmented corneal rings in non-Wilsonian liver disease. | lld:pubmed |
| pubmed-article:842986 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:842986 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:842986 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:842986 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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