| pubmed-article:8422354 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8422354 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
| pubmed-article:8422354 | lifeskim:mentions | umls-concept:C0026383 | lld:lifeskim |
| pubmed-article:8422354 | lifeskim:mentions | umls-concept:C0994334 | lld:lifeskim |
| pubmed-article:8422354 | lifeskim:mentions | umls-concept:C2825575 | lld:lifeskim |
| pubmed-article:8422354 | lifeskim:mentions | umls-concept:C0332516 | lld:lifeskim |
| pubmed-article:8422354 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8422354 | pubmed:dateCreated | 1993-2-23 | lld:pubmed |
| pubmed-article:8422354 | pubmed:abstractText | A structure for the triple helix d(T)n.d(A)n.d(T)n consistent with recent infrared spectral data is proposed, and its salient features are discussed. The present structure preserves the pseudodyad between the Watson-Crick base-paired adenine and thymine strands and in addition has a pseudorotational symmetry relating the Hoogsteen-paired adenine and thymine strands. The simultaneous presence of these two symmetries gives rise to a dyad between the two thymine polynucleotides. These symmetries result in identical backbone conformations for all three strands, unlike any previously proposed model for a triple helix. The proposed structure has an axial rise per residue of 3.26 A and 12 residues per turn obtained from X-ray fiber diffraction [Arnott S., & Selsing, E. (1974) J. Mol. Biol. 88, 509-521]. The present structure is structurally and conformationally similar to double helical B-form DNA and has sugar pucker in the C2'-endo region. This structure is fundamentally different from the one proposed by Arnott and co-workers, which was based on structural and conformational features similar to double helical A-form DNA with C3'-endo sugar pucker. It is stereochemically satisfactory, and it does not have the disallowed nonbonded distances present in the earlier model of Arnott and co-workers. It is energetically much more favorable than their structure. Coordinates of the present structure are given. | lld:pubmed |
| pubmed-article:8422354 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8422354 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8422354 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8422354 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8422354 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8422354 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8422354 | pubmed:issn | 0006-2960 | lld:pubmed |
| pubmed-article:8422354 | pubmed:author | pubmed-author:MilesH THT | lld:pubmed |
| pubmed-article:8422354 | pubmed:author | pubmed-author:SasisekharanV... | lld:pubmed |
| pubmed-article:8422354 | pubmed:author | pubmed-author:RaghunathanGG | lld:pubmed |
| pubmed-article:8422354 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8422354 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:8422354 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:8422354 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8422354 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8422354 | pubmed:pagination | 455-62 | lld:pubmed |
| pubmed-article:8422354 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:meshHeading | pubmed-meshheading:8422354-... | lld:pubmed |
| pubmed-article:8422354 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8422354 | pubmed:articleTitle | Symmetry and molecular structure of a DNA triple helix: d(T)n.d(A)n.d(T)n. | lld:pubmed |
| pubmed-article:8422354 | pubmed:affiliation | Laboratory of Mathematical Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892. | lld:pubmed |
| pubmed-article:8422354 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8422354 | lld:pubmed |
