pubmed-article:8418010 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8418010 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:8418010 | lifeskim:mentions | umls-concept:C0032019 | lld:lifeskim |
pubmed-article:8418010 | lifeskim:mentions | umls-concept:C0033371 | lld:lifeskim |
pubmed-article:8418010 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:8418010 | pubmed:dateCreated | 1993-2-4 | lld:pubmed |
pubmed-article:8418010 | pubmed:abstractText | Twenty-two consecutive cases of adenoma in acromegalic patients were studied immunohistochemically. All the tumors contained prolactin (PRL)-reactive cells (3% to 53% of the total number of tumor cells) as well as growth hormone (GH)-reactive cells (4% to 74% of the total number of tumor cells). All acromegalic cases studied were thus plurihormonal adenomas containing GH and PRL; no pure GH cell adenoma was present. Twenty cases were further examined at the ultrastructural level in conjunction with postembedding double-labeling immunoelectron microscopy; 15 of these cases were diagnosed as mixed GH cell-PRL cell adenomas. The previously diagnosed pure GH cell adenomas possibly may have contained PRL cells and thus should be considered as mixed GH cell-PRL cell adenomas. Mammosomatotroph adenomas were rare in this series. Double-labeling immunoelectron microscopy, using protein A gold particles of two different sizes, greatly facilitated the distinction among GH, PRL, and mammosomatotroph cells. | lld:pubmed |
pubmed-article:8418010 | pubmed:language | eng | lld:pubmed |
pubmed-article:8418010 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8418010 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8418010 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8418010 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8418010 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8418010 | pubmed:month | Jan | lld:pubmed |
pubmed-article:8418010 | pubmed:issn | 0046-8177 | lld:pubmed |
pubmed-article:8418010 | pubmed:author | pubmed-author:KameyaTT | lld:pubmed |
pubmed-article:8418010 | pubmed:author | pubmed-author:ToyaSS | lld:pubmed |
pubmed-article:8418010 | pubmed:author | pubmed-author:OtaniMM | lld:pubmed |
pubmed-article:8418010 | pubmed:author | pubmed-author:FuruhataSS | lld:pubmed |
pubmed-article:8418010 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8418010 | pubmed:volume | 24 | lld:pubmed |
pubmed-article:8418010 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8418010 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8418010 | pubmed:pagination | 10-5 | lld:pubmed |
pubmed-article:8418010 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8418010 | pubmed:meshHeading | pubmed-meshheading:8418010-... | lld:pubmed |
pubmed-article:8418010 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8418010 | pubmed:articleTitle | Prolactin presents in all pituitary tumors of acromegalic patients. | lld:pubmed |
pubmed-article:8418010 | pubmed:affiliation | Department of Pathology, Kitasato University School of Medicine, Kanagawa, Japan. | lld:pubmed |
pubmed-article:8418010 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8418010 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |