| pubmed-article:8399497 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0009663 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0086287 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0032334 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0086582 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0037633 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C1382100 | lld:lifeskim |
| pubmed-article:8399497 | lifeskim:mentions | umls-concept:C0544341 | lld:lifeskim |
| pubmed-article:8399497 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8399497 | pubmed:dateCreated | 1993-10-25 | lld:pubmed |
| pubmed-article:8399497 | pubmed:abstractText | The efficacy and safety of topical treatment for external condylomata acuminata with either self-applied 0.5% podophyllotoxin (PT) or hospital-applied 25% podophyllin (PODO) solution was compared in 138 males and 67 females in an open multicentre study. After one week of treatment, wart clearance was observed in 53% of males and 37% of females in the PT group as compared with 19% of males and 19% of females in the PODO group (P < 0.001 in males; P = 0.13 in females). At 5 weeks after commencing treatment, clearance of warts had been achieved in 86% males and 72% females in the PT group as compared with 78% of males and 62% females in the PODO group (P = 0.08 in males; P = 0.14 in females). Treatment had cleared 81% of 180 treated sites in all PT recipients as compared with 61% of 95 treated sites in all PODO recipients (P < 0.001). The increased speed of action of PT was associated with an increased incidence of symptoms and signs of inflammation at treatment sites in both males and females (P < 0.001). These were generally mild, did not interfere with continuing treatment, and were more frequent in those patients whose warts were eradicated most rapidly. Home-based treatment with 0.5% podophyllotoxin lotion in appropriately instructed patients of either sex is superior in efficacy to outpatient applied 25% podophyllin and has the potential to reduce the number of hospital attendances required in genital wart eradication. | lld:pubmed |
| pubmed-article:8399497 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8399497 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8399497 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8399497 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:8399497 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8399497 | pubmed:issn | 0956-4624 | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:DrakeSS | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:KinghornG RGR | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:McMillanAA | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:BinghamJ SJS | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:MulcahyFF | lld:pubmed |
| pubmed-article:8399497 | pubmed:author | pubmed-author:LaceyCC | lld:pubmed |
| pubmed-article:8399497 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8399497 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:8399497 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8399497 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8399497 | pubmed:pagination | 194-9 | lld:pubmed |
| pubmed-article:8399497 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8399497 | pubmed:articleTitle | An open, comparative, study of the efficacy of 0.5% podophyllotoxin lotion and 25% podophyllotoxin solution in the treatment of condylomata acuminata in males and females. | lld:pubmed |
| pubmed-article:8399497 | pubmed:affiliation | Department of Genitourinary Medicine, Royal Hallamshire Hospital, Sheffield, UK. | lld:pubmed |
| pubmed-article:8399497 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8399497 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:8399497 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8399497 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
| pubmed-article:8399497 | pubmed:publicationType | Multicenter Study | lld:pubmed |
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