| pubmed-article:8390683 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C1419053 | lld:lifeskim |
| pubmed-article:8390683 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:8390683 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8390683 | pubmed:dateCreated | 1993-7-22 | lld:pubmed |
| pubmed-article:8390683 | pubmed:abstractText | Recently, the successful cloning of a receptor for platelet-activating factor (PAF), a lipid mediator of inflammation, was reported. Here we investigated the distribution and potential diversity of human PAF receptors (hPAF-Rs) among individual leukocyte populations by (i) hPAF-R mRNA transcription studies and (ii) analysis of cell surface expression of hPAF-R protein using a polyclonal anti-peptide antibody (anti-hPAF-R164-173). Northern blot analysis, flow cytometry, and immunoblotting with anti-hPAF-R antibody indicated that monocytic, neutrophilic, and B-lymphocytic cell lines all shared a similar hPAF-R species, whereas resting T-cell and natural killer cell lines failed to express detectable levels of either hPAF-R protein or mRNA. Peripheral blood leukocyte populations showed a distribution of hPAF-R cell surface expression similar to that of the corresponding cell lines. Furthermore, binding of anti-hPAF-R164-173 antiserum, purified IgG, or Fab and F(ab')2 fragments to the receptor of all investigated PAF-R-positive cell lines induced an increase in intracellular free calcium concentration. The characterization of the expression of a lipid ligand receptor using antibodies against an intrinsic portion of the receptor protein has, to our knowledge, never been reported previously. | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8390683 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8390683 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8390683 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8390683 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:8390683 | pubmed:author | pubmed-author:MüllerEE | lld:pubmed |
| pubmed-article:8390683 | pubmed:author | pubmed-author:Rola-Pleszczy... | lld:pubmed |
| pubmed-article:8390683 | pubmed:author | pubmed-author:AlamiNN | lld:pubmed |
| pubmed-article:8390683 | pubmed:author | pubmed-author:DagenaisPP | lld:pubmed |
| pubmed-article:8390683 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8390683 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8390683 | pubmed:volume | 90 | lld:pubmed |
| pubmed-article:8390683 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8390683 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8390683 | pubmed:pagination | 5818-22 | lld:pubmed |
| pubmed-article:8390683 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
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| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
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| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
| pubmed-article:8390683 | pubmed:meshHeading | pubmed-meshheading:8390683-... | lld:pubmed |
| pubmed-article:8390683 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8390683 | pubmed:articleTitle | Identification and functional characterization of platelet-activating factor receptors in human leukocyte populations using polyclonal anti-peptide antibody. | lld:pubmed |
| pubmed-article:8390683 | pubmed:affiliation | Department of Pediatrics, Faculty of Medicine, Université de Sherbrooke, Canada. | lld:pubmed |
| pubmed-article:8390683 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8390683 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8390683 | lld:pubmed |
