pubmed-article:8388556 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0005810 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0205070 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0405581 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
pubmed-article:8388556 | lifeskim:mentions | umls-concept:C0019721 | lld:lifeskim |
pubmed-article:8388556 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:8388556 | pubmed:dateCreated | 1993-6-22 | lld:pubmed |
pubmed-article:8388556 | pubmed:abstractText | Clinical observations, epidemiologic data, and results of animal experiments support the theory of genetic anticipation of testicular germ-cell tumors. Attempts to find genetic markers of testicular cancer have yielded conflicting results. We studied blood groups of 577 patients treated for testicular germ-cell tumor (GCT) and controls. Lewis antigens of 143 patients treated for testicular GCT, and controls, and HLA antigens of 215 patients treated for testicular GCT and controls. Blood-group frequencies were the same in patients and controls. Lewis antigen Le(a-b-) was more frequent in patients than in controls (p = 0.046; RR = 2.38). HLA Bw41 was associated with seminoma (p = 0.0001; RR = 8.2). None of the previously reported associations of other HLA antigens with GCT was confirmed. We found no association of HLA antigens with susceptibility to metastatic disease. The associations of Le(a-b-) with testicular GCT and of HLA Bw41 with seminoma support the contention that genetic factors are involved in the etiology and pathogenesis of GCT. HLA-Bw41 could possibly be employed as a risk marker for seminoma. | lld:pubmed |
pubmed-article:8388556 | pubmed:language | eng | lld:pubmed |
pubmed-article:8388556 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8388556 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8388556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8388556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8388556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8388556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8388556 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8388556 | pubmed:issn | 0030-2414 | lld:pubmed |
pubmed-article:8388556 | pubmed:author | pubmed-author:DieckmannK... | lld:pubmed |
pubmed-article:8388556 | pubmed:author | pubmed-author:BünteSS | lld:pubmed |
pubmed-article:8388556 | pubmed:author | pubmed-author:KlänRR | lld:pubmed |
pubmed-article:8388556 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8388556 | pubmed:volume | 50 | lld:pubmed |
pubmed-article:8388556 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8388556 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8388556 | pubmed:pagination | 252-8 | lld:pubmed |
pubmed-article:8388556 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:8388556 | pubmed:meshHeading | pubmed-meshheading:8388556-... | lld:pubmed |
pubmed-article:8388556 | pubmed:meshHeading | pubmed-meshheading:8388556-... | lld:pubmed |
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pubmed-article:8388556 | pubmed:meshHeading | pubmed-meshheading:8388556-... | lld:pubmed |
pubmed-article:8388556 | pubmed:meshHeading | pubmed-meshheading:8388556-... | lld:pubmed |
pubmed-article:8388556 | pubmed:meshHeading | pubmed-meshheading:8388556-... | lld:pubmed |
pubmed-article:8388556 | pubmed:articleTitle | HLA antigens, Lewis antigens, and blood groups in patients with testicular germ-cell tumors. | lld:pubmed |
pubmed-article:8388556 | pubmed:affiliation | Department of Urology, Klinikum Steglitz, Freie Universität Berlin, FRG. | lld:pubmed |
pubmed-article:8388556 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8388556 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8388556 | lld:pubmed |