Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8374771rdf:typepubmed:Citationlld:pubmed
pubmed-article:8374771lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:8374771lifeskim:mentionsumls-concept:C0019564lld:lifeskim
pubmed-article:8374771lifeskim:mentionsumls-concept:C0005910lld:lifeskim
pubmed-article:8374771lifeskim:mentionsumls-concept:C0043094lld:lifeskim
pubmed-article:8374771lifeskim:mentionsumls-concept:C0332157lld:lifeskim
pubmed-article:8374771lifeskim:mentionsumls-concept:C0304403lld:lifeskim
pubmed-article:8374771pubmed:issue1-2lld:pubmed
pubmed-article:8374771pubmed:dateCreated1993-10-20lld:pubmed
pubmed-article:8374771pubmed:abstractTextThere is increasing evidence that early exposure to psychostimulants exerts long-lasting effects on the central nervous system. Yet, analysis of the body weight gain and volumetric determinations of brain areas have not been performed by comparing the effects of neonatal exposure to cocaine and amphetamine. Male (Wistar) rats were given cocaine hydrochloride (15 mg/kg body weight/day), D-amphetamine sulphate (25 mg/kg body weight/day) or saline, s.c., twice daily, from postnatal day (PND) 1 to 30. The experimental design used random permuted blocks of 4 males per litter -9 litters for body weight gain evolution and 9 for the analysis of body, brain and cerebellum at PND30. Volumes of the hippocampal formation were calculated in horizontal serial sections of celloidin embedded material from 6 animals per group. The analysis of body weight gain evolution was performed using discriminant functions and allowed the separation of the amphetamine group from the remainder and the control from the psychostimulants group; weight gain in PND 24-30 period presented the highest discriminating power. The mean volume of the hippocampal formation was lower in the psychostimulants group, and the differences were significant in the molecular layer of the dentate gyrus of cocaine and amphetamine exposed animals when compared with the controls.(ABSTRACT TRUNCATED AT 250 WORDS)lld:pubmed
pubmed-article:8374771pubmed:languageenglld:pubmed
pubmed-article:8374771pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8374771pubmed:citationSubsetIMlld:pubmed
pubmed-article:8374771pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8374771pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8374771pubmed:statusMEDLINElld:pubmed
pubmed-article:8374771pubmed:monthAuglld:pubmed
pubmed-article:8374771pubmed:issn0006-8993lld:pubmed
pubmed-article:8374771pubmed:authorpubmed-author:SilvaM CMClld:pubmed
pubmed-article:8374771pubmed:authorpubmed-author:TavaresM AMAlld:pubmed
pubmed-article:8374771pubmed:issnTypePrintlld:pubmed
pubmed-article:8374771pubmed:day13lld:pubmed
pubmed-article:8374771pubmed:volume619lld:pubmed
pubmed-article:8374771pubmed:ownerNLMlld:pubmed
pubmed-article:8374771pubmed:authorsCompleteYlld:pubmed
pubmed-article:8374771pubmed:pagination137-45lld:pubmed
pubmed-article:8374771pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:meshHeadingpubmed-meshheading:8374771-...lld:pubmed
pubmed-article:8374771pubmed:year1993lld:pubmed
pubmed-article:8374771pubmed:articleTitleBody weight gain and hippocampal volumes of rats exposed neonatally to psychostimulants.lld:pubmed
pubmed-article:8374771pubmed:affiliationInstitute of Anatomy, Medical School of Porto, Portugal.lld:pubmed
pubmed-article:8374771pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8374771pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8374771lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8374771lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8374771lld:pubmed