| pubmed-article:8369488 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C0017626 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C0004112 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C1882598 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C0036579 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C0597879 | lld:lifeskim |
| pubmed-article:8369488 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:8369488 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:8369488 | pubmed:dateCreated | 1993-10-8 | lld:pubmed |
| pubmed-article:8369488 | pubmed:abstractText | L-deprenyl is a selective inhibitor of monoamine oxidase (MAO) B, an enzyme predominantly localized in astrocytes. We have investigated the effect of treatment with L-deprenyl (0.25 mg kg-1 day-1) on glial fibrillary acidic protein (GFAP) immunoreactivity (IR) after lesioning the rat striatum with an injection cannula. No effect of drug treatment on GFAP IR was found in unlesioned striata. A significant increase (p < 0.01 vs saline treated rats) in GFAP IR was found in the tissue surrounding the lesion in striata of rats treated with L-deprenyl for 4 days after the lesion. When post-treated for 42 days, however, L-deprenyl no longer increased GFAP IR although reactive astrocytes were still present in the lesioned area. These results suggest that L-deprenyl can enhance the activation of astrocytes during a critical time-period following a striatal injury. | lld:pubmed |
| pubmed-article:8369488 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8369488 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8369488 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8369488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8369488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8369488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8369488 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8369488 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8369488 | pubmed:issn | 0959-4965 | lld:pubmed |
| pubmed-article:8369488 | pubmed:author | pubmed-author:FuxeKK | lld:pubmed |
| pubmed-article:8369488 | pubmed:author | pubmed-author:AgnatiL FLF | lld:pubmed |
| pubmed-article:8369488 | pubmed:author | pubmed-author:BiaginiGG | lld:pubmed |
| pubmed-article:8369488 | pubmed:author | pubmed-author:ZoliMM | lld:pubmed |
| pubmed-article:8369488 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8369488 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:8369488 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8369488 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8369488 | pubmed:pagination | 955-8 | lld:pubmed |
| pubmed-article:8369488 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:meshHeading | pubmed-meshheading:8369488-... | lld:pubmed |
| pubmed-article:8369488 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8369488 | pubmed:articleTitle | L-deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain. | lld:pubmed |
| pubmed-article:8369488 | pubmed:affiliation | Department of Human Physiology, University of Modena, Italy. | lld:pubmed |
| pubmed-article:8369488 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8369488 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8369488 | lld:pubmed |
