| pubmed-article:8361628 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8361628 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8361628 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8361628 | lifeskim:mentions | umls-concept:C0001962 | lld:lifeskim |
| pubmed-article:8361628 | lifeskim:mentions | umls-concept:C0751214 | lld:lifeskim |
| pubmed-article:8361628 | lifeskim:mentions | umls-concept:C0599946 | lld:lifeskim |
| pubmed-article:8361628 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:8361628 | pubmed:dateCreated | 1993-9-27 | lld:pubmed |
| pubmed-article:8361628 | pubmed:abstractText | Recent observations using acute and persistent pain models have suggested that activation of the N-methyl-D-aspartate (NMDA) receptor is required for mechanisms that underly the development and maintenance of thermal hyperalgesia. The present results document that both NMDA-mediated thermal hyperalgesia produced after acute intrathecal NMDA administration and NMDA-mediated thermal hyperalgesia produced in a model of neuropathic pain are dose-dependently and reversibly attenuated by intrathecal administration of ethanol (0.5-1.0%; total dose, 106-213 nmol, i.t.). This is consistent with recent reports that ethanol may function as a selective NMDA receptor antagonist at low concentrations and further extends the evidence that thermal hyperalgesia is mediated by NMDA receptors. | lld:pubmed |
| pubmed-article:8361628 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8361628 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8361628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8361628 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8361628 | pubmed:month | May | lld:pubmed |
| pubmed-article:8361628 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:8361628 | pubmed:author | pubmed-author:GebhartG FGF | lld:pubmed |
| pubmed-article:8361628 | pubmed:author | pubmed-author:MellerS TST | lld:pubmed |
| pubmed-article:8361628 | pubmed:author | pubmed-author:DykstraCC | lld:pubmed |
| pubmed-article:8361628 | pubmed:author | pubmed-author:MavesT JTJ | lld:pubmed |
| pubmed-article:8361628 | pubmed:author | pubmed-author:PechmanP SPS | lld:pubmed |
| pubmed-article:8361628 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8361628 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:8361628 | pubmed:volume | 154 | lld:pubmed |
| pubmed-article:8361628 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8361628 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8361628 | pubmed:pagination | 137-40 | lld:pubmed |
| pubmed-article:8361628 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:meshHeading | pubmed-meshheading:8361628-... | lld:pubmed |
| pubmed-article:8361628 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8361628 | pubmed:articleTitle | Ethanol dose-dependently attenuates NMDA-mediated thermal hyperalgesia in the rat. | lld:pubmed |
| pubmed-article:8361628 | pubmed:affiliation | Department of Pharmacology, University of Iowa, Iowa City 52242. | lld:pubmed |
| pubmed-article:8361628 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8361628 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8361628 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
