pubmed-article:8360479 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0017355 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0019744 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C1521970 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0037813 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0009609 | lld:lifeskim |
pubmed-article:8360479 | lifeskim:mentions | umls-concept:C0205227 | lld:lifeskim |
pubmed-article:8360479 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:8360479 | pubmed:dateCreated | 1993-9-28 | lld:pubmed |
pubmed-article:8360479 | pubmed:abstractText | Microcapillary HPLC electrospray ionization tandem mass spectrometry was used to sequence 15 peptides eluted from HLA-B7. Sequence alignment implicated four peptide positions in specific interactions with the class I molecule, and their importance was confirmed using synthetic peptides. Because no crystal structure for HLA-B7 was available, computer-assisted modeling was used to understand novel aspects of peptide binding specificity and to accurately predict the effect of defined changes in peptide structure. The results demonstrate that mass-spectrometric sequencing coupled with computer-assisted modeling can be used in the absence of a crystal structure to make accurate predictions concerning requirements for peptide binding to class I molecules. These techniques may be valuable to predict or engineer T cell epitopes. | lld:pubmed |
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pubmed-article:8360479 | pubmed:language | eng | lld:pubmed |
pubmed-article:8360479 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8360479 | pubmed:citationSubset | AIM | lld:pubmed |
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pubmed-article:8360479 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8360479 | pubmed:month | Sep | lld:pubmed |
pubmed-article:8360479 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:SakaguchiKK | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:BenjaminDD | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:AppellaEE | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:EngelhardV... | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:HuntD FDF | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:HendersonR... | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:ShabanowitzJJ | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:ZhuN ZNZ | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:HuczkoE LEL | lld:pubmed |
pubmed-article:8360479 | pubmed:author | pubmed-author:BodnarW MWM | lld:pubmed |
pubmed-article:8360479 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8360479 | pubmed:day | 1 | lld:pubmed |
pubmed-article:8360479 | pubmed:volume | 151 | lld:pubmed |
pubmed-article:8360479 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8360479 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8360479 | pubmed:pagination | 2572-87 | lld:pubmed |
pubmed-article:8360479 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:8360479 | pubmed:meshHeading | pubmed-meshheading:8360479-... | lld:pubmed |
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pubmed-article:8360479 | pubmed:meshHeading | pubmed-meshheading:8360479-... | lld:pubmed |
pubmed-article:8360479 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8360479 | pubmed:articleTitle | Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling. | lld:pubmed |
pubmed-article:8360479 | pubmed:affiliation | Beirne Carter Center for Immunology Research, University of Virginia, Charlottesville 22901. | lld:pubmed |
pubmed-article:8360479 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8360479 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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