| pubmed-article:8322969 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0037929 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0005682 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C2330261 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:8322969 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:8322969 | pubmed:issue | 6 Pt 2 | lld:pubmed |
| pubmed-article:8322969 | pubmed:dateCreated | 1993-8-5 | lld:pubmed |
| pubmed-article:8322969 | pubmed:abstractText | Spinal cord injury (SCI) in humans results in inappropriate contractions of the external urethral sphincter muscle (EUS) during micturition (bladder-sphincter dyssynergia), leading to urinary retention. The major goal of this study was to determine whether SCI in rats has similar detrimental effects on micturition. After chronic SCI, urethan-anesthetized rats had a significantly (15-fold) increased bladder capacity and impaired voiding (31-fold increase in residual volume) compared with control rats. Bladder contractions in SCI rats were accompanied by abnormal tonic EUS electromyographic activity, whereas the EUS electromyograms of control rats exhibited a burst pattern (4-8 Hz) during voiding. Suppression of EUS activity with neuromuscular blockade did not improve the fraction of urine voided in SCI rats and reduced the fraction voided in control rats. Therefore, both tonic activity and complete quiescence of the rat's EUS appear to be detrimental to voiding, suggesting that the normal bursting EUS activity facilitates bladder emptying. In summary, rats and humans exhibit similar micturition dysfunctions after SCI (e.g., bladder-sphincter dyssynergia and impaired voiding). | lld:pubmed |
| pubmed-article:8322969 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8322969 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8322969 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8322969 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8322969 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8322969 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8322969 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8322969 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:8322969 | pubmed:author | pubmed-author:de GroatW CWC | lld:pubmed |
| pubmed-article:8322969 | pubmed:author | pubmed-author:KruseM NMN | lld:pubmed |
| pubmed-article:8322969 | pubmed:author | pubmed-author:BeltonA LAL | lld:pubmed |
| pubmed-article:8322969 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8322969 | pubmed:volume | 264 | lld:pubmed |
| pubmed-article:8322969 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8322969 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8322969 | pubmed:pagination | R1157-63 | lld:pubmed |
| pubmed-article:8322969 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:meshHeading | pubmed-meshheading:8322969-... | lld:pubmed |
| pubmed-article:8322969 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8322969 | pubmed:articleTitle | Changes in bladder and external urethral sphincter function after spinal cord injury in the rat. | lld:pubmed |
| pubmed-article:8322969 | pubmed:affiliation | Department of Pharmacology, University of Pittsburgh, Pennsylvania 15261. | lld:pubmed |
| pubmed-article:8322969 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8322969 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8322969 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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