| pubmed-article:8318425 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0009402 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0019764 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0278250 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0442821 | lld:lifeskim |
| pubmed-article:8318425 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8318425 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8318425 | pubmed:dateCreated | 1993-7-30 | lld:pubmed |
| pubmed-article:8318425 | pubmed:abstractText | One hundred large bowel carcinomas operated on between 1978 and 1982 were studied immunohistochemically with regard to expression of HLA-DR antigens. Three sections from each tumour were investigated by a semiquantitative scoring system, and a mean score for each patient established. Based on this scoring system, the tumours were divided into three groups: 0; 0.1-1.0; and > 1.0. All patients were followed until death (n = 68) or until June 1, 1992, and all cancer-specific deaths (n = 56) have been recorded. Analysis of survival in the whole patient group showed significant difference between the three levels of tumour HLA-DR expression (P = 0.006); patients who had tumours with strong HLA-DR expression showing the best survival. In a stratified analysis after Dukes' stages there was still a significant difference (P > 0.001) between the three levels of HLA-DR staining intensity. After a multiple regression analysis (Cox) with correction for different variables, the HLA-DR expression maintained its significance as a risk factor. To our knowledge this is the first time a relationship between intensity of tumour DR expression and survival has been shown in large bowel carcinoma. | lld:pubmed |
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| pubmed-article:8318425 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:8318425 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8318425 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8318425 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8318425 | pubmed:issn | 0007-0920 | lld:pubmed |
| pubmed-article:8318425 | pubmed:author | pubmed-author:LundEE | lld:pubmed |
| pubmed-article:8318425 | pubmed:author | pubmed-author:RognumT OTO | lld:pubmed |
| pubmed-article:8318425 | pubmed:author | pubmed-author:HaugeSS | lld:pubmed |
| pubmed-article:8318425 | pubmed:author | pubmed-author:AndersenS NSN | lld:pubmed |
| pubmed-article:8318425 | pubmed:author | pubmed-author:MelingG IGI | lld:pubmed |
| pubmed-article:8318425 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8318425 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:8318425 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8318425 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8318425 | pubmed:pagination | 80-5 | lld:pubmed |
| pubmed-article:8318425 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8318425 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8318425 | pubmed:articleTitle | Strong HLA-DR expression in large bowel carcinomas is associated with good prognosis. | lld:pubmed |
| pubmed-article:8318425 | pubmed:affiliation | Institute of Forensic Medicine, National Hospital, University of Oslo, Norway. | lld:pubmed |
| pubmed-article:8318425 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8318425 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8318425 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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