| pubmed-article:8315356 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C0085236 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C0238607 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C1521725 | lld:lifeskim |
| pubmed-article:8315356 | lifeskim:mentions | umls-concept:C0205375 | lld:lifeskim |
| pubmed-article:8315356 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8315356 | pubmed:dateCreated | 1993-7-23 | lld:pubmed |
| pubmed-article:8315356 | pubmed:abstractText | Manifestations of pulmonary disease in pediatric AIDS patients differ from those in adults. To evaluate whether differences in the frequency of alveolar macrophage (AM) infection with human immunodeficiency virus type 1 (HIV-1) could account for these clinical distinctions, we undertook a comparative analysis of HIV-1 DNA in AMs from pediatric and adult AIDS patients by enzymatic amplification. A higher frequency of viral DNA detection in pediatric cases (100%) compared with adults (67%) was observed. The sensitivity of detection was 1 viral DNA copy per 4000 AMs; matched peripheral blood mononuclear cells from six of seven pediatric and eight of nine adult patients tested HIV-1 DNA positive. Adult but not pediatric patients exhibited a marked alveolar lymphocytosis, 32% mean lymphocyte count compared with 7.0%, respectively. These results suggest that the burden of HIV-1 in the lungs of pediatric AIDS patients is greater than that in adults. | lld:pubmed |
| pubmed-article:8315356 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8315356 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8315356 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8315356 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8315356 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8315356 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8315356 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8315356 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8315356 | pubmed:issn | 0741-5400 | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:NowakowskaEE | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:EdenEE | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:PotashM JMJ | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:SteinerPP | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:VolskyD JDJ | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:ShahabuddinMM | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:HuangZ BZB | lld:pubmed |
| pubmed-article:8315356 | pubmed:author | pubmed-author:PearceT ETE | lld:pubmed |
| pubmed-article:8315356 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8315356 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:8315356 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8315356 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8315356 | pubmed:pagination | 722-6 | lld:pubmed |
| pubmed-article:8315356 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
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| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:meshHeading | pubmed-meshheading:8315356-... | lld:pubmed |
| pubmed-article:8315356 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8315356 | pubmed:articleTitle | Uniform detection of HIV-1 in alveolar macrophages of pediatric but not adult AIDS patients. | lld:pubmed |
| pubmed-article:8315356 | pubmed:affiliation | Molecular Virology Laboratory, St. Luke's/Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10019. | lld:pubmed |
| pubmed-article:8315356 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8315356 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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