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| pubmed-article:8259665 | lifeskim:mentions | umls-concept:C0001747 | lld:lifeskim |
| pubmed-article:8259665 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8259665 | pubmed:dateCreated | 1994-1-18 | lld:pubmed |
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| pubmed-article:8259665 | pubmed:abstractText | A study of simian T-cell lymphoma/leukemia virus infection, conducted on 747 nonhuman primates belonging to 14 different species in Central and Western Africa, indicated that 4 species (Cercopithecus aethiops, Erythrocebus patas, Papio doguera, and Cercopithecus mona pogonias) had a high prevalence of seropositivity to simian T-cell lymphoma/leukemia virus type I (STLV-I). The other nonhuman primate species, however, had negative or low levels of anti-HTLV-I antibodies. STLV-I pol and env DNA was detected in 12 of 12 different animals among the seropositive species. However, STLV-I pX DNA could be detected in only 10 of 12 animals. Comparative phylogenetic analyses based on 140 bp sequence of the pol gene indicate that these STLV-I isolates were 0-9% divergent from each other and were 3.5-7% divergent from the prototype related human retrovirus HTLV-I (ATK). The West African STLV-I isolates formed a unique phylogenetic cluster as did most of the Central African STLV-I isolates, save for STLV-I (Tan 90). The phylogenetic data indicate that cross species transmission of HTLV-I and STLV-I continued to occur long after their ancestral strain separated from the progenitor to HTLV-II. Comparative amino acid analyses indicated that there was marked conservation of the TAX protein regardless of host species, while the pol and REX proteins exhibited increasing levels of diversity. | lld:pubmed |
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| pubmed-article:8259665 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8259665 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8259665 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8259665 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8259665 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8259665 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:DubeSS | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:LoveJ LJL | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:MathiotCC | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:DurandJ PJP | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:MullerM CMC | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:HervaRR | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:LeguennoBB | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:SaksenaN KNK | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:DiopO MOM | lld:pubmed |
| pubmed-article:8259665 | pubmed:author | pubmed-author:DigouetteJ... | lld:pubmed |
| pubmed-article:8259665 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8259665 | pubmed:volume | 198 | lld:pubmed |
| pubmed-article:8259665 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8259665 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:8259665 | pubmed:pagination | 297-310 | lld:pubmed |
| pubmed-article:8259665 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:8259665 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8259665 | pubmed:articleTitle | Seroepidemiologic, molecular, and phylogenetic analyses of simian T-cell leukemia viruses (STLV-I) from various naturally infected monkey species from central and western Africa. | lld:pubmed |
| pubmed-article:8259665 | pubmed:affiliation | Department of Medicine, SUNY Health Science Center, Syracuse 13210. | lld:pubmed |
| pubmed-article:8259665 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8259665 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8259665 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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