| pubmed-article:8249285 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C0026591 | lld:lifeskim |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C0031437 | lld:lifeskim |
| pubmed-article:8249285 | lifeskim:mentions | umls-concept:C1521797 | lld:lifeskim |
| pubmed-article:8249285 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8249285 | pubmed:dateCreated | 1993-12-23 | lld:pubmed |
| pubmed-article:8249285 | pubmed:abstractText | The aim of this study was to investigate if the risk of mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) is influenced by the biological phenotype of the mother's virus. Virus isolates from 30 HIV-1 infected mothers and 12 infected children born to these mothers were analyzed for replication on several cell lines (Jurkat-tat, Jurkat, CEM, U937 clone 2, and MT-2). We show that mothers who harbor virus able to replicate in cell lines (rapid/high virus) have a significantly higher risk to infect their children than mothers with slow/low virus (P = 0.017). Children born to mothers with rapid/high viruses can be infected by slow/low as well as rapid/high viruses, while mothers with slow/low virus appear to transmit slow/low virus in every case. Our study shows that the biological phenotype of the mother's virus may serve as a complementary marker to CD4+ lymphocyte counts and p24 antigenemia in predicting the risk of transmission of HIV-1 to the child. | lld:pubmed |
| pubmed-article:8249285 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8249285 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8249285 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8249285 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8249285 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8249285 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8249285 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:RossiPP | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:AlbertJJ | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:FenyöE MEM | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:ScarlattiGG | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:BucceriAA | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:HodaraVV | lld:pubmed |
| pubmed-article:8249285 | pubmed:author | pubmed-author:MuggiascaLL | lld:pubmed |
| pubmed-article:8249285 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8249285 | pubmed:volume | 197 | lld:pubmed |
| pubmed-article:8249285 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8249285 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8249285 | pubmed:pagination | 624-9 | lld:pubmed |
| pubmed-article:8249285 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8249285 | pubmed:meshHeading | pubmed-meshheading:8249285-... | lld:pubmed |
| pubmed-article:8249285 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8249285 | pubmed:articleTitle | Transmission of human immunodeficiency virus type 1 (HIV-1) from mother to child correlates with viral phenotype. | lld:pubmed |
| pubmed-article:8249285 | pubmed:affiliation | Department of Virology, Karolinska Institute, Stockholm, Sweden. | lld:pubmed |
| pubmed-article:8249285 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8249285 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8249285 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8249285 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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