pubmed-article:8241671 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8241671 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
pubmed-article:8241671 | lifeskim:mentions | umls-concept:C0205653 | lld:lifeskim |
pubmed-article:8241671 | lifeskim:mentions | umls-concept:C0007570 | lld:lifeskim |
pubmed-article:8241671 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
pubmed-article:8241671 | lifeskim:mentions | umls-concept:C0038995 | lld:lifeskim |
pubmed-article:8241671 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:8241671 | pubmed:dateCreated | 1994-1-6 | lld:pubmed |
pubmed-article:8241671 | pubmed:abstractText | The aim of this study was to determine the minimum prevalence of coeliac disease in a group of 459 diabetic children and adolescents. Six patients were already known to have coeliac disease. A total of 436 patients with type 1 diabetes mellitus aged 2-21 years and with age at onset at 2 months to 17 years at three paediatric departments agreed to participate in the study. All patients were tested for gliadin IgA antibodies with a commercial kit (Pharmacia Gluten IgA EIA). Later, serum was tested for reticulin IgA/IgG antibodies. Nineteen patients had elevated gliadin IgA levels (> 25 AU). Eighteen underwent jejunal biopsy. Ten had total or subtotal villous atrophy. These 10 patients were reticulin IgA-positive. Of 417 gliadin IgA-negative patients, 408 were reticulin IgA/IgG-negative. Of 6 reticulin IgA-positive patients, 3 had total or subtotal villous atrophy. All 3 had become gliadin IgA-positive at the time of biopsy. Among 3 reticulin IgG-positive patients with IgA deficiency, 2 had total villous atrophy: 1 was not willing to be biopsied. Patients with total or subtotal villous atrophy were judged as having coeliac disease and were recommended a gluten-free diet. Within 2 months, gliadin IgA levels were normal in patients adhering to the diet. Five patients have gone through a second jejunal biopsy to date with normal histology in all 5. The 15 newly diagnosed patients with coeliac disease plus 6 already known patients with coeliac disease and type 1 diabetes mellitus gave a minimum prevalence of coeliac disease in diabetic children and adolescents of 21/459 = 4.6%. | lld:pubmed |
pubmed-article:8241671 | pubmed:language | eng | lld:pubmed |
pubmed-article:8241671 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8241671 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8241671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8241671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8241671 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8241671 | pubmed:month | Sep | lld:pubmed |
pubmed-article:8241671 | pubmed:issn | 0803-5253 | lld:pubmed |
pubmed-article:8241671 | pubmed:author | pubmed-author:JohanssonCC | lld:pubmed |
pubmed-article:8241671 | pubmed:author | pubmed-author:LannerAA | lld:pubmed |
pubmed-article:8241671 | pubmed:author | pubmed-author:VianderMM | lld:pubmed |
pubmed-article:8241671 | pubmed:author | pubmed-author:ElfstrandP... | lld:pubmed |
pubmed-article:8241671 | pubmed:author | pubmed-author:SigursNN | lld:pubmed |
pubmed-article:8241671 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8241671 | pubmed:volume | 82 | lld:pubmed |
pubmed-article:8241671 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8241671 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8241671 | pubmed:pagination | 748-51 | lld:pubmed |
pubmed-article:8241671 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:8241671 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8241671 | pubmed:articleTitle | Prevalence of coeliac disease in diabetic children and adolescents in Sweden. | lld:pubmed |
pubmed-article:8241671 | pubmed:affiliation | Department of Pediatrics, Bordås Hospital, Sweden. | lld:pubmed |
pubmed-article:8241671 | pubmed:publicationType | Journal Article | lld:pubmed |
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