| pubmed-article:8227411 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C0014644 | lld:lifeskim |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C0007874 | lld:lifeskim |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C0205282 | lld:lifeskim |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C0221198 | lld:lifeskim |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:8227411 | lifeskim:mentions | umls-concept:C1514391 | lld:lifeskim |
| pubmed-article:8227411 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:8227411 | pubmed:dateCreated | 1993-12-14 | lld:pubmed |
| pubmed-article:8227411 | pubmed:abstractText | AIM--To detect the presence or absence of Epstein-Barr virus (EBV) in cervical lesions ranging from normality to invasive malignancy. METHODS--Eighteen randomly selected cases of invasive squamous cell carcinomas of the uterine cervix were examined as well as 25 cases each of normal cervices and those showing cervical intra-epithelial neoplasia (CIN) I, II, and III. DNA-DNA in situ hybridisation, using a biotinylated probe to the Bam H1 "W" fragment of EBV, was carried out in addition to the polymerase chain reaction using specific primer sequences that flank a 153 base pair segment of the Bam H1 "W" region of the EBV genome and which do not cross-amplify other DNA herpes viruses. Positive control material included paraffin wax embedded P3 HR1 lymphoblastoid cells (containing high copy numbers of EBV) and two nasopharyngeal carcinomas positive for EBV. RESULTS--Neither normal nor CIN I tissue was positive. Eight per cent of CIN II tissue was positive; 8% of CIN III, and 43% of carcinomas were positive for EBV. CONCLUSION--The study shows that the virus is present in some cases of cervical carcinoma and to a lesser degree in some premalignant lesions of the cervix, but the exact association between it and cervical oncogenesis, be it causative or incidental, remains to be determined. | lld:pubmed |
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| pubmed-article:8227411 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8227411 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8227411 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8227411 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8227411 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8227411 | pubmed:issn | 0021-9746 | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:BurkeLL | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:LewisF AFA | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:O'BrienDD | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:CrowleyMM | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:KealyW FWF | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:HealyII | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:HoganJJ | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:AnnisPP | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:O'LearyJ JJJ | lld:pubmed |
| pubmed-article:8227411 | pubmed:author | pubmed-author:LandersR JRJ | lld:pubmed |
| pubmed-article:8227411 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8227411 | pubmed:volume | 46 | lld:pubmed |
| pubmed-article:8227411 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8227411 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:8227411 | pubmed:pagination | 931-5 | lld:pubmed |
| pubmed-article:8227411 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8227411 | pubmed:meshHeading | pubmed-meshheading:8227411-... | lld:pubmed |
| pubmed-article:8227411 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8227411 | pubmed:articleTitle | Epstein-Barr virus in normal, pre-malignant, and malignant lesions of the uterine cervix. | lld:pubmed |
| pubmed-article:8227411 | pubmed:affiliation | Department of Pathology, University College Cork, Ireland. | lld:pubmed |
| pubmed-article:8227411 | pubmed:publicationType | Journal Article | lld:pubmed |
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