| pubmed-article:8220175 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8220175 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:8220175 | lifeskim:mentions | umls-concept:C0039067 | lld:lifeskim |
| pubmed-article:8220175 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:8220175 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:8220175 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:8220175 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8220175 | pubmed:dateCreated | 1993-12-14 | lld:pubmed |
| pubmed-article:8220175 | pubmed:abstractText | A combination of the stopped-flow technology with dual channel spectrofluorometry of Ca(2+)-indicators was utilized for the measurement of rapid Ca(2+)-signals in rat cerebral cortical synaptosomes evoked by K(+)-depolarization. There was no observable contribution of Ca(2+)-ions from intracellular stores to the rise in [Ca2+]i. The kinetics of the fast increase in intracellular Ca2+ concentration was analysed in relation to the depolarization strength. The maximal increase in [Ca2+]i and the time course of Ca(2+)-channel inactivation were determined for depolarizations obtained by different extracellular K(+)-concentrations ([K+]o). An apparent threshold was observed at about 18 mM [K+]o; a maximal Ca(2+)-signal amplitude was estimated at about 40 mM [K+]o. Pharmacological properties of the involved Ca(2+)-channels were determined using selective Ca(2+)-channel blockers (Dihydropyridines, omega-Conotoxin, omega-Agatoxins); the results suggest that a P-type voltage-dependent Ca(2+)-channel is the relevant channel type, generating the evoked Ca(2+)-signals in rat cerebral cortical synaptosomes. | lld:pubmed |
| pubmed-article:8220175 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8220175 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8220175 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8220175 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8220175 | pubmed:issn | 0197-0186 | lld:pubmed |
| pubmed-article:8220175 | pubmed:author | pubmed-author:BreerHH | lld:pubmed |
| pubmed-article:8220175 | pubmed:author | pubmed-author:AdamsMM | lld:pubmed |
| pubmed-article:8220175 | pubmed:author | pubmed-author:SchochJJ | lld:pubmed |
| pubmed-article:8220175 | pubmed:author | pubmed-author:TareilusEE | lld:pubmed |
| pubmed-article:8220175 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8220175 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:8220175 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8220175 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8220175 | pubmed:pagination | 331-41 | lld:pubmed |
| pubmed-article:8220175 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:meshHeading | pubmed-meshheading:8220175-... | lld:pubmed |
| pubmed-article:8220175 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8220175 | pubmed:articleTitle | Analysis of rapid calcium signals in synaptosomes. | lld:pubmed |
| pubmed-article:8220175 | pubmed:affiliation | University Stuttgart-Hohenheim, Institute of Zoophysiology, Germany. | lld:pubmed |
| pubmed-article:8220175 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8220175 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8220175 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8220175 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8220175 | lld:pubmed |
