| pubmed-article:8202502 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0030054 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0020980 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0597177 | lld:lifeskim |
| pubmed-article:8202502 | lifeskim:mentions | umls-concept:C0162524 | lld:lifeskim |
| pubmed-article:8202502 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8202502 | pubmed:dateCreated | 1994-7-6 | lld:pubmed |
| pubmed-article:8202502 | pubmed:abstractText | A method for monitoring formation of latex particle pairs by chemiluminescence is described. Molecular oxygen is excited by a photosensitizer and an antenna dye that are dissolved in one of the particles. 1 delta gO2 diffuses to the second particle and initiates a high quantum yield chemiluminescent reaction of an olefin that is dissolved in it. The efficiency of 1 delta gO2 transfer between particles is approximately 3.5%. The technique permits real-time measurement of particle binding kinetics. Second-order rate constants increase with the number of receptor binding sites on the particles and approach diffusion control. By using antibody-coated particles, a homogeneous immunoassay capable of detecting approximately 4 amol of thyroid-stimulating hormone in 12 min was demonstrated. Single molecules of analyte produce particle heterodimers that are detected even when no larger aggregates are formed. | lld:pubmed |
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| pubmed-article:8202502 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8202502 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8202502 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8202502 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8202502 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8202502 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:DaffornAA | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:SinghSS | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:UllmanE FEF | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:YuiYY | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:SwitchenkoA... | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:IrvineJ DJD | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:SkoldC NCN | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:KirakossianHH | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:IrvinB RBR | lld:pubmed |
| pubmed-article:8202502 | pubmed:author | pubmed-author:PeaseJ SJS | lld:pubmed |
| pubmed-article:8202502 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8202502 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:8202502 | pubmed:volume | 91 | lld:pubmed |
| pubmed-article:8202502 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8202502 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:8202502 | pubmed:pagination | 5426-30 | lld:pubmed |
| pubmed-article:8202502 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:8202502 | pubmed:meshHeading | pubmed-meshheading:8202502-... | lld:pubmed |
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| pubmed-article:8202502 | pubmed:meshHeading | pubmed-meshheading:8202502-... | lld:pubmed |
| pubmed-article:8202502 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8202502 | pubmed:articleTitle | Luminescent oxygen channeling immunoassay: measurement of particle binding kinetics by chemiluminescence. | lld:pubmed |
| pubmed-article:8202502 | pubmed:affiliation | Research Department, Syva Company, Palo Alto, CA 94303. | lld:pubmed |
| pubmed-article:8202502 | pubmed:publicationType | Journal Article | lld:pubmed |
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