| pubmed-article:8180808 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0002708 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0030095 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0312418 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:8180808 | lifeskim:mentions | umls-concept:C0036667 | lld:lifeskim |
| pubmed-article:8180808 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:8180808 | pubmed:dateCreated | 1994-6-16 | lld:pubmed |
| pubmed-article:8180808 | pubmed:abstractText | Central nucleus (Ce), basomedial and medial nuclei of the amygdala (AMG), and some parts of the striato-pallidal system, present high densities of oxytocin (OT)-binding sites. In order to examine whether these OT-binding sites are functional receptors, the OT neuronal sensitivity and the presence of OT-binding sites were investigated using electrophysiological and autoradiographical techniques. To identify the AMG cells, electrical stimulation of the oval subnucleus of the bed nucleus of the stria terminalis (Ov) and of the parabrachial nucleus (Pb) were performed. Somatic and auditory sensory stimulations were also tested. OT was applied by iontophoresis during extracellular single unit recordings of cells which were localized in frontal brain sections subsequently used for histoautoradiographic detection of OT-binding sites. Cells responding to Ov nucleus stimulation were located in the AMG, mainly in the Ce nucleus, whereas those responding to Pb nucleus stimulation were distributed in the Ce nucleus and in the postero lateral part of the caudate putamen. Iontophoretic OT application excited 45% of the recorded cells (43/96) among which OT alone activated spontaneous firing rate of 30 and potentiated the L-Glutamate (GLU)-induced activation on 13. These OT-sensitive neurons were located mainly in the AMG and caudate putamen areas containing OT-binding sites. These results strongly suggest that OT-binding sites found in the AMG are functional receptors upon which OT could act as a neurotransmitter and as a neuromodulator to regulate autonomic functions. | lld:pubmed |
| pubmed-article:8180808 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8180808 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8180808 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8180808 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8180808 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8180808 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8180808 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8180808 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:8180808 | pubmed:author | pubmed-author:Condés-LaraMM | lld:pubmed |
| pubmed-article:8180808 | pubmed:author | pubmed-author:Freund-Mercie... | lld:pubmed |
| pubmed-article:8180808 | pubmed:author | pubmed-author:VeinantePP | lld:pubmed |
| pubmed-article:8180808 | pubmed:author | pubmed-author:RabaiMM | lld:pubmed |
| pubmed-article:8180808 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8180808 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:8180808 | pubmed:volume | 637 | lld:pubmed |
| pubmed-article:8180808 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8180808 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8180808 | pubmed:pagination | 277-86 | lld:pubmed |
| pubmed-article:8180808 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
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| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:meshHeading | pubmed-meshheading:8180808-... | lld:pubmed |
| pubmed-article:8180808 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8180808 | pubmed:articleTitle | Correlation between oxytocin neuronal sensitivity and oxytocin-binding sites in the amygdala of the rat: electrophysiological and histoautoradiographic study. | lld:pubmed |
| pubmed-article:8180808 | pubmed:affiliation | Laboratoire de Physiologie Générale, Université Louis Pasteur, URA, CNRS 1446, Strasbourg, France. | lld:pubmed |
| pubmed-article:8180808 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8180808 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8180808 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8180808 | lld:pubmed |
