| pubmed-article:8150087 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0025936 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0086519 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8150087 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8150087 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8150087 | pubmed:dateCreated | 1994-5-12 | lld:pubmed |
| pubmed-article:8150087 | pubmed:abstractText | Adult-type hypolactasia is a genetic condition making approximately one half of the human population intolerant to milk because of abdominal symptoms. The cause is a post-weaning down-regulation of the intestinal-specific enzyme lactase-phlorizin hydrolase (LPH) reducing the intestinal capacity to hydrolyze lactose. We here demonstrate that the stretch -17 to -994 in the pig LPH-promoter carries cis-elements which direct a small intestinal-specific expression and a post-weaning decline of a linked rabbit beta-globin gene. These data demonstrate that the post-weaning decline of LPH is mainly due to a transcriptional down-regulation. | lld:pubmed |
| pubmed-article:8150087 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8150087 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8150087 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8150087 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8150087 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8150087 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8150087 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8150087 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:SjöströmHH | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:NorénOO | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:PrydzHH | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:OlsenJJ | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:HansenG HGH | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:TroelsenJ TJT | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:MehlumAA | lld:pubmed |
| pubmed-article:8150087 | pubmed:author | pubmed-author:SpodsbergNN | lld:pubmed |
| pubmed-article:8150087 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8150087 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:8150087 | pubmed:volume | 342 | lld:pubmed |
| pubmed-article:8150087 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8150087 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8150087 | pubmed:pagination | 291-6 | lld:pubmed |
| pubmed-article:8150087 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:meshHeading | pubmed-meshheading:8150087-... | lld:pubmed |
| pubmed-article:8150087 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8150087 | pubmed:articleTitle | 1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice. | lld:pubmed |
| pubmed-article:8150087 | pubmed:affiliation | Department of Medical Biochemistry and Genetics, Panum Institute, University of Copenhagen, Denmark. | lld:pubmed |
| pubmed-article:8150087 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8150087 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:407244 | entrezgene:pubmed | pubmed-article:8150087 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8150087 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8150087 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8150087 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8150087 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8150087 | lld:pubmed |
