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pubmed-article:8148401pubmed:abstractTextWe developed an enzyme-linked immunosorbent assay (ELISA) for vascular endothelial growth factor/vascular permeability factor (VEGF/VPF). The assay revealed that VEGF/VPF levels in the sera of mice were significantly increased from undetectable level by s.c. transplantation with a solid tumor. We also measured VEGF/VPF levels in serum specimens obtained from cancer patients with several types of cancers. VEGF/VPF levels in the sera from cancer patients were significantly higher than those in the sera from the individuals with no sign of cancer.lld:pubmed
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pubmed-article:8148401pubmed:articleTitleVascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients.lld:pubmed
pubmed-article:8148401pubmed:affiliationBioscience Research Department, Toagosei Chemical Industry Tsukuba Research Laboratory, Ibaraki, Japan.lld:pubmed
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