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pubmed-article:8120099 | lifeskim:mentions | umls-concept:C0004359 | lld:lifeskim |
pubmed-article:8120099 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
pubmed-article:8120099 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:8120099 | pubmed:dateCreated | 1994-4-4 | lld:pubmed |
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pubmed-article:8120099 | pubmed:abstractText | We report the identification and primary sequence of PCM-1, a 228-kD centrosomal protein that exhibits a distinct cell cycle-dependent association with the centrosome complex. Immunofluorescence microscopy using antibodies against recombinant PCM-1 demonstrated that PCM-1 is tightly associated with the centrosome complex through G1, S, and a portion of G2. However, late in G2, as cells prepare for mitosis, PCM-1 dissociates from the centrosome and then remains dispersed throughout the cell during mitosis before re-associating with the centrosomes in the G1 phase progeny cells. These results demonstrate that the pericentriolar material is a dynamic substance whose composition can fluctuate during the cell cycle. | lld:pubmed |
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pubmed-article:8120099 | pubmed:language | eng | lld:pubmed |
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pubmed-article:8120099 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:8120099 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8120099 | pubmed:month | Mar | lld:pubmed |
pubmed-article:8120099 | pubmed:issn | 0021-9525 | lld:pubmed |
pubmed-article:8120099 | pubmed:author | pubmed-author:BanSS | lld:pubmed |
pubmed-article:8120099 | pubmed:author | pubmed-author:ZimmerW EWE | lld:pubmed |
pubmed-article:8120099 | pubmed:author | pubmed-author:BalczonRR | lld:pubmed |
pubmed-article:8120099 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8120099 | pubmed:volume | 124 | lld:pubmed |
pubmed-article:8120099 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8120099 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8120099 | pubmed:pagination | 783-93 | lld:pubmed |
pubmed-article:8120099 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:8120099 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:8120099 | pubmed:articleTitle | PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution. | lld:pubmed |
pubmed-article:8120099 | pubmed:affiliation | Department of Structural and Cellular Biology, University of South Alabama, Mobile 36688. | lld:pubmed |
pubmed-article:8120099 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8120099 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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