| pubmed-article:8108224 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0121772 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0231330 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0028959 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0042210 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0036043 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C1521725 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:8108224 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:8108224 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8108224 | pubmed:dateCreated | 1994-3-22 | lld:pubmed |
| pubmed-article:8108224 | pubmed:abstractText | The safety of the combined oligosaccharide conjugate Haemophilus influenzae (Hib) type b (HbOC) and whole cell diphtheria-tetanus toxoids-pertussis (DTP) vaccine (Tetramune, HbOC-DTP; Lederle) in infancy was evaluated in 6644 recipients of this vaccine and compared with 3914 recipients of separate injections of whole cell DTP and HbOC vaccines when given as a three dose regimen to infants at 2, 4 and 6 months of age in each group. Of the total number of infants in the study, a subset of 1435 were enrolled into the study and then randomly assigned to receive either the Hib-DPT combined vaccine or the separate components. This subset was used to assess local and systemic side effects which were evaluated utilizing telephone interviews 48 to 72 hours after vaccine. The remaining children in the study population were enrolled in a nonrandomized manner. For these children parents were offered the experimental Hib-DPT vaccine and refusers were given HbOC and DTP. Both of these groups of children as well as the randomized subset described above were used to assess rates of episodes of hospitalization, emergency room utilization and sudden infant death syndrome in HbOC-DTP recipients and children who received HbOC and DTP separately. Immunogenicity was evaluated in 123 children by collection of a single serum sample 30 days after the third dose of HbOC-DTP. The observed immunogenicity was comparable to that observed in other recent studies for HbOC and DTP component antigens. The profile of local and systemic side effects observed was virtually identical to that observed after DTP plus HbOC given separately.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:8108224 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8108224 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8108224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8108224 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8108224 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8108224 | pubmed:issn | 0891-3668 | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:JohnsonC LCL | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:ShinefieldH... | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:LewisE MEM | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:HackellJ GJG | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:BlackS BSB | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:RayPP | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:HiattRR | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:FiremanBB | lld:pubmed |
| pubmed-article:8108224 | pubmed:author | pubmed-author:MadoreD VDV | lld:pubmed |
| pubmed-article:8108224 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8108224 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:8108224 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8108224 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8108224 | pubmed:pagination | 981-5 | lld:pubmed |
| pubmed-article:8108224 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:meshHeading | pubmed-meshheading:8108224-... | lld:pubmed |
| pubmed-article:8108224 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8108224 | pubmed:articleTitle | Safety of combined oligosaccharide conjugate Haemophilus influenzae type b (HbOC) and whole cell diphtheria-tetanus toxoids-pertussis vaccine in infancy. The Kaiser Permanente Pediatric Vaccine Study Group. | lld:pubmed |
| pubmed-article:8108224 | pubmed:affiliation | Kaiser Permanente Medical Center, Oakland, CA 94611. | lld:pubmed |
| pubmed-article:8108224 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8108224 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:8108224 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:8108224 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8108224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8108224 | lld:pubmed |
