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pubmed-article:8105088pubmed:abstractTextThe antigenic closeness between the chimpanzee alloantigen Rc of the R-C-E-F system, and the human alloantigen Rho(D) suggests a phyloge-connection between their genes. To confirm at the molecular level the common origin of these genes, genomic DNA from 16 unrelated chimpanzees of various R-C-E-F phenotypes were digested by three restriction enzymes and analyzed by Southern blot using a human Rh cDNA probe and three exon-specific probes. Restrictions profiles displayed reach polymorphism. Correlations between some bands and certain R-C-E-F phenotypes demonstrate that the human Rh cDNA probe defines in chimpanzee genomic DNA some genes of the R-C-E-F system.lld:pubmed
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pubmed-article:8105088pubmed:articleTitleRelationship between chimpanzee Rh-like genes and the R-C-E-F blood group system.lld:pubmed
pubmed-article:8105088pubmed:affiliationCentre Régional de Transfusion Sanguine, CHU Purpan, Toulouse, France.lld:pubmed
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