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pubmed-article:8100211pubmed:abstractTextG6PD Konan and G6PD Ube are the most common glucose-6-phosphate dehydrogenase (G6PD) variants found in Japan. To clarify the molecular abnormality of these two variants, the entire coding region was amplified by polymerase chain reaction from genomic DNA (G6PD Konan) or cDNA (G6PD Ube). Direct sequencing revealed that both variants have the same nucleotide substitution (241 C to T) in exon 4, which predicts an Arg to Cys substitution at amino acid 81.lld:pubmed
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pubmed-article:8100211pubmed:articleTitleMolecular abnormality of G6PD Konan and G6PD Ube, the most common glucose-6-phosphate dehydrogenase variants in Japan.lld:pubmed
pubmed-article:8100211pubmed:affiliationOkinaka Memorial Institute for Medical Research, Tokyo, Japan.lld:pubmed
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