| pubmed-article:8095488 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C0020202 | lld:lifeskim |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C0242957 | lld:lifeskim |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C0002085 | lld:lifeskim |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C0679932 | lld:lifeskim |
| pubmed-article:8095488 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:8095488 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8095488 | pubmed:dateCreated | 1993-4-14 | lld:pubmed |
| pubmed-article:8095488 | pubmed:abstractText | Nucleotide sequence analysis of the ERBB2 proton-oncogene in human breast tumors revealed a sequence variation at codons 654 and 655, corresponding to the transmembrane region of the protein. To investigate this polymorphism, genotyping of 340 unrelated individuals was conducted by allele-specific oligonucleotide (ASO) hybridization of DNA amplified from the ERBB2 transmembrane region. ASO hybridization under competition conditions allowed rapid and unambiguous assignment of alleles and revealed the occurrence of a new allele, B3, encoding Val-Val. The sensitivity and the specificity of the ASO competition hybridization technique indicate that the method is generally applicable to the analysis of polymorphisms in the human genome. | lld:pubmed |
| pubmed-article:8095488 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8095488 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8095488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8095488 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8095488 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8095488 | pubmed:issn | 0888-7543 | lld:pubmed |
| pubmed-article:8095488 | pubmed:author | pubmed-author:WallaceR BRB | lld:pubmed |
| pubmed-article:8095488 | pubmed:author | pubmed-author:WuA MAM | lld:pubmed |
| pubmed-article:8095488 | pubmed:author | pubmed-author:WuL TLT | lld:pubmed |
| pubmed-article:8095488 | pubmed:author | pubmed-author:EhsaniAA | lld:pubmed |
| pubmed-article:8095488 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8095488 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:8095488 | pubmed:geneSymbol | ERBB2 | lld:pubmed |
| pubmed-article:8095488 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8095488 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8095488 | pubmed:pagination | 426-9 | lld:pubmed |
| pubmed-article:8095488 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:meshHeading | pubmed-meshheading:8095488-... | lld:pubmed |
| pubmed-article:8095488 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8095488 | pubmed:articleTitle | Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization. | lld:pubmed |
| pubmed-article:8095488 | pubmed:affiliation | Department of Molecular Biochemistry, Beckman Research Institute of the City of Hope, Duarte, California 91010-0269. | lld:pubmed |
| pubmed-article:8095488 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8095488 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| literatureCitation:567_8095... | literatureCitation:pubmed | pubmed-article:8095488 | lld:drugbank |
| entrez-gene:2064 | entrezgene:pubmed | pubmed-article:8095488 | lld:entrezgene |
