Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8035203rdf:typepubmed:Citationlld:pubmed
pubmed-article:8035203lifeskim:mentionsumls-concept:C0001554lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0034721lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0017651lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0014298lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0035696lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0018546lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0066908lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C1280500lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0442805lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0851285lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0205263lld:lifeskim
pubmed-article:8035203lifeskim:mentionsumls-concept:C0443252lld:lifeskim
pubmed-article:8035203pubmed:issue2lld:pubmed
pubmed-article:8035203pubmed:dateCreated1994-8-12lld:pubmed
pubmed-article:8035203pubmed:abstractTextThe mRNA encoding mu-opioid receptors is expressed in neurons of the globus pallidus, a region of the basal ganglia that receives a dense enkephalinergic innervation from the striatum. The regulation of the mRNAs encoding the opioid peptide enkephalin in the striatum and the mu-opioid receptor in the globus pallidus was examined with in situ hybridization histochemistry following short- or long-term haloperidol treatments, which alter striatal enkephalin mRNA levels. Animals were administered haloperidol daily for 3 or 7 days (1 mg/kg, s.c.) or continuously for 8 months (1 mg/kg, depot followed by oral). Enkephalin and mu-opioid receptor mRNA levels were unchanged after 3 days of haloperidol treatment. In contrast, the enkephalin mRNA level was increased in the striatum, and mu-opioid receptor mRNA levels were markedly decreased in the globus pallidus after 7 days of haloperidol administration. Similar effects were observed in rats treated with haloperidol for 8 months. The results provide the first evidence of regulation of mu-opioid receptor mRNA in vivo.lld:pubmed
pubmed-article:8035203pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:languageenglld:pubmed
pubmed-article:8035203pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:citationSubsetIMlld:pubmed
pubmed-article:8035203pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8035203pubmed:statusMEDLINElld:pubmed
pubmed-article:8035203pubmed:monthAuglld:pubmed
pubmed-article:8035203pubmed:issn0022-3042lld:pubmed
pubmed-article:8035203pubmed:authorpubmed-author:YuLLlld:pubmed
pubmed-article:8035203pubmed:authorpubmed-author:ReisineTTlld:pubmed
pubmed-article:8035203pubmed:authorpubmed-author:EllisonG DGDlld:pubmed
pubmed-article:8035203pubmed:authorpubmed-author:ChesseletM...lld:pubmed
pubmed-article:8035203pubmed:authorpubmed-author:DelfsJ MJMlld:pubmed
pubmed-article:8035203pubmed:issnTypePrintlld:pubmed
pubmed-article:8035203pubmed:volume63lld:pubmed
pubmed-article:8035203pubmed:ownerNLMlld:pubmed
pubmed-article:8035203pubmed:authorsCompleteYlld:pubmed
pubmed-article:8035203pubmed:pagination777-80lld:pubmed
pubmed-article:8035203pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:meshHeadingpubmed-meshheading:8035203-...lld:pubmed
pubmed-article:8035203pubmed:year1994lld:pubmed
pubmed-article:8035203pubmed:articleTitleRegulation of mu-opioid receptor mRNA in rat globus pallidus: effects of enkephalin increases induced by short- and long-term haloperidol administration.lld:pubmed
pubmed-article:8035203pubmed:affiliationDepartment of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia 19104.lld:pubmed
pubmed-article:8035203pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8035203pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:8035203pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8035203lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8035203lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8035203lld:pubmed