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pubmed-article:8014381pubmed:abstractTextThe aim of this study was to characterize the distribution of GABAergic cells in the rat gut mucosa. Thin and/or thick serial sections of segments of rat antrum and distal colon were treated for autoradiographic localization of sites of [3H]GABA (50 nM) high-affinity uptake, or GABA immunoreactivity. Dense accumulations of silver grains were localized to a discrete population of granulated mucosal cells. These appeared to be D-type endocrine cells. These gut regions also displayed strongly GABA-immunoreactive mucosal cells. These results confirm the presence of GABAergic cells in the rat antral mucosa, and reveal that [3H]GABA is accumulated by mucosal endocrine cells in the rat colon.lld:pubmed
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pubmed-article:8014381pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:8014381pubmed:year1994lld:pubmed
pubmed-article:8014381pubmed:articleTitle[3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon.lld:pubmed
pubmed-article:8014381pubmed:affiliationDepartment of Physiology, University of Ottawa, Ontario, Canada.lld:pubmed
pubmed-article:8014381pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8014381pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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