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pubmed-article:8002808pubmed:abstractTextThe authors present the neuropathological and clinical findings of four cases of ceroid lipofuscinosis or Batten's disease. In two cases the autopsy findings showed brain atrophy and nerve cells packed with cytoplasmic granules compatible with lipofuscin. One case was diagnosed by histochemical techniques in frozen sections of rectal biopsy which showed myoenteric ganglion cells with cytoplasmic acid phosphatase positive material as well as numerous macrophages filled with lipofuscin in the mucosae. The fourth case diagnosed by electron microscopy of conjunctival biopsy which showed cytoplasmic inclusions of membranous, curvilinear and fingerprint types.lld:pubmed
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pubmed-article:8002808pubmed:authorpubmed-author:BruceCClld:pubmed
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pubmed-article:8002808pubmed:authorpubmed-author:TorresL FLFlld:pubmed
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pubmed-article:8002808pubmed:dateRevised2009-11-11lld:pubmed
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pubmed-article:8002808pubmed:year1994lld:pubmed
pubmed-article:8002808pubmed:articleTitle[Neuronal ceroid-lipofuscinosis. Report of 4 cases with study by rectal histochemistry, conjunctiva electron microscopy and necropsy].lld:pubmed
pubmed-article:8002808pubmed:affiliationUnidade de Neuropatologia e Microscopia Eletrônica, Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba, Brasil.lld:pubmed
pubmed-article:8002808pubmed:publicationTypeJournal Articlelld:pubmed
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