| pubmed-article:7998672 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7998672 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7998672 | lifeskim:mentions | umls-concept:C0681829 | lld:lifeskim |
| pubmed-article:7998672 | lifeskim:mentions | umls-concept:C0060440 | lld:lifeskim |
| pubmed-article:7998672 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7998672 | pubmed:dateCreated | 1995-1-19 | lld:pubmed |
| pubmed-article:7998672 | pubmed:abstractText | In 3-month-old Wistar rats carrageenan and CCl4 injected intraperitoneally induce an acute phase reaction which is characterized by a marked increase in alpha 1, alpha 2, beta serum globulins. This reaction corresponds to a large increase in these globulins in the first case and a smaller one in the second. A lipoperoxidant effect is demonstrated by the serum lipoprotein mobility as the lipoperoxidation index (in MDA units) or the decrease in serum vitamin A and E concentrations. This effect is also greater in the first case than in the second one. In the same way the lipoperoxidant effect is shown in liver microsomes but with a lower amplitude in the first case than in the second one. The treatment of rats by intraperitoneal injection of diosmine (150 mg/kg per week) during the 8 weeks which precede the injection of carrageenan or CCl4 results in: i) a marked decrease in the acute-phase reaction and a lower one in the lipoperoxidant effect, in serum; ii) a decrease in the CCl4 induced lipoperoxidant effect in liver microsomes. It may be concluded that diosmine, not injected at the same time as carrageenan or CCl4, but during the previous 8 weeks is sufficiently well distributed in the whole body to produce a marked inhibition of the acute phase reaction and a perceptible effect on lipoperoxidation. It may be considered an effective complement to the natural antioxidant defences of the organism (vitamins A and E). | lld:pubmed |
| pubmed-article:7998672 | pubmed:language | fre | lld:pubmed |
| pubmed-article:7998672 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7998672 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7998672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7998672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7998672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7998672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7998672 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7998672 | pubmed:issn | 0003-3898 | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:ClercMM | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:ThomasM JMJ | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:DumonM FMF | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:PeuchantEE | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:CarbonneauM... | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:PerromatAA | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:MelinA MAM | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:DubourgLL | lld:pubmed |
| pubmed-article:7998672 | pubmed:author | pubmed-author:Freneix-Clerc... | lld:pubmed |
| pubmed-article:7998672 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7998672 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:7998672 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7998672 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7998672 | pubmed:pagination | 171-7 | lld:pubmed |
| pubmed-article:7998672 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:meshHeading | pubmed-meshheading:7998672-... | lld:pubmed |
| pubmed-article:7998672 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7998672 | pubmed:articleTitle | [In vivo study of the antilipoperoxidant effect of 3',5,7-trihydroxy-4'-methoxy flavone 7 rutinoside]. | lld:pubmed |
| pubmed-article:7998672 | pubmed:affiliation | Laboratoire de biochimie médicale A, université de Bordeaux II, France. | lld:pubmed |
| pubmed-article:7998672 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7998672 | pubmed:publicationType | English Abstract | lld:pubmed |
