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pubmed-article:7988914pubmed:abstractTextThe glucan-binding lectins of Streptococcus cricetus AHT and Streptococcus sobrinus 6715 were reversibly inhibited by sodium fluoride. Fluoride was superior to chloride, bromide, iodide and thiocyanate in preventing glucan-mediated aggregation of the bacteria. Fluoride was also an effective inhibitor of the sucrose-dependent adhesion of S. sobrinus to glass surfaces. The inhibition of glucan-binding lectin activities may be one of the mechanisms of action of fluoride in preventing dental disease.lld:pubmed
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pubmed-article:7988914pubmed:authorpubmed-author:TaylorK GKGlld:pubmed
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pubmed-article:7988914pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:7988914pubmed:articleTitleFluoride inhibits the glucan-binding lectin of Streptococcus sobrinus.lld:pubmed
pubmed-article:7988914pubmed:affiliationDepartment of Microbiology and Immunology, University of Louisville, KY 40292.lld:pubmed
pubmed-article:7988914pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7988914pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed