| pubmed-article:7956951 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C1257743 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C0079189 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C0245514 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C0333348 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C1159884 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:7956951 | lifeskim:mentions | umls-concept:C1292733 | lld:lifeskim |
| pubmed-article:7956951 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:7956951 | pubmed:dateCreated | 1994-12-16 | lld:pubmed |
| pubmed-article:7956951 | pubmed:abstractText | Tumor necrosis factor (TNF) is implicated in wasting syndromes and insulin resistance in chronic infection and obese-linked diabetes. TNF (10 ng/ml) inhibited adipocyte differentiation of 3T3-L1 cells, and in these TNF treated cells little insulin-stimulated glucose uptake was observed. Treatment of 3T3-L1 cells with troglitazone (1-10 microM) partially prevented this inhibitory effect of TNF on adipogenesis, and enhanced expression of C/EBP alpha and GLUT4, even in the presence of TNF. Troglitazone also prevented the inhibitory effects of interleukin-1, interleukin-6, and leukemia inhibitory factor, but not of transforming growth factor beta on adipocyte differentiation of 3T3-L1 cells. These effects might contribute to the antidiabetic effect of troglitazone in obese diabetic animals. | lld:pubmed |
| pubmed-article:7956951 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:7956951 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:7956951 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7956951 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:7956951 | pubmed:issn | 0013-7227 | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:SakakibaraSS | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:YoshiokaSS | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:FujiwaraTT | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:YamaguchiJJ | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:HorikoshiHH | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:SerizawaNN | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:OhsumiJJ | lld:pubmed |
| pubmed-article:7956951 | pubmed:author | pubmed-author:MiyadaiKK | lld:pubmed |
| pubmed-article:7956951 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7956951 | pubmed:volume | 135 | lld:pubmed |
| pubmed-article:7956951 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7956951 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7956951 | pubmed:pagination | 2279-82 | lld:pubmed |
| pubmed-article:7956951 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:7956951 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7956951 | pubmed:articleTitle | Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells. | lld:pubmed |
| pubmed-article:7956951 | pubmed:affiliation | Biomedical Research Laboratories, Sankyo Co. Ltd., Tokyo, Japan. | lld:pubmed |
| pubmed-article:7956951 | pubmed:publicationType | Journal Article | lld:pubmed |
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